ArticleAbdominal radiology (New York)2020
Higher frequency of hepatic steatosis at CT among COVID-19-positive patients.
Article in Abdominal radiology (New York), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
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Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- The eyes see what the mind seeks: a systematic review of abdominal imaging findings in patients with COVID-19.The British journal of radiology · 2021Pooled it
- Entropy-Based CT Radiomics as an Imaging Marker of Hepatic Injury in COVID-19.Diagnostics (Basel, Switzerland) · 2025Article
- Altered liver hemodynamics in patients with COVID-19: a cross sectional study.Journal of ultrasound · 2025Article
- The effect of metabolic dysfunction-associated steatotic liver disease on the disease progression in patients with COVID-19 associated pneumonia.Translational gastroenterology and hepatology · 2025Article
- Comparison of liver fibrosis scores and fatty liver on computed tomography as risk factors for severity of COVID-19.JGH open : an open access journal of gastroenterology and hepatology · 2024Article
- Deep-learning segmentation to select liver parenchyma for categorizing hepatic steatosis on multinational chest CT.Scientific reports · 2024Article
- Is Steatotic Liver Disease Related to Poor Outcome in COVID-19-Hospitalized Patients?Journal of clinical medicine · 2024Article
- Role of CT-based body composition parameters in the course of COVID-19.Turkish journal of medical sciences · 2024Article
- Liver Damage and Impaired Coagulation in COVID-19 Patients: A Case Series.Diseases (Basel, Switzerland) · 2023Article
- Article
- Diagnostic and Therapeutic Radiology of the GI Tract, Liver, and Pancreas in Patients with COVID.Gastroenterology clinics of North America · 2023Review
- Increased Incidence of Pancreatic Steatosis Detected Using Computed Tomography at Initial Diagnosis of Coronavirus Disease 2019.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023Article
- Liver injury in COVID-19 patients with non-alcoholic fatty liver disease: an update.Archives of medical sciences. Atherosclerotic diseases · 2023Article
- Pancreatic Steatosis Evaluated by Automated Volumetric CT Fat Fraction of the Pancreas: Association with Severity in COVID-19 Pneumonia.Tomography (Ann Arbor, Mich.) · 2022Article
- Article
- May an incidental finding on chest CT be a predictor of access in intensive care unit? Role of hepatic steatosis in patients affected by SARS-CoV-2.Journal of public health research · 2022Article
- NAFLD determined by Dallas Steatosis Index is associated with poor outcomes in COVID-19 pneumonia: a cohort study.Internal and emergency medicine · 2022Article
- Post-COVID-19 Liver Injury: Comprehensive Imaging With Multiparametric Ultrasound.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2022Article
- COVID-19 pathophysiology and ultrasound imaging: A multiorgan review.Journal of clinical ultrasound : JCU · 2022Review
- Prognostic factors of worse outcome for hospitalized COVID-19 patients, with emphasis on chest computed tomography data: a retrospective study.Einstein (Sao Paulo, Brazil) · 2022Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeRecent studies have demonstrated that obesity is significantly associated with increased disease severity, hospitalizations and mortality in COVID-19, with a potential role in the pathogenesis and prevalence in the new pandemic. The association with hepatic steatosis, however, a condition closely related to obesity within the spectrum of systemic metabolic dysfunctions, remains to be elucidated. We aimed to evaluate the frequency of hepatic steatosis as incidentally detected in chest CT examinations of COVID-19 positive patients in comparison to non-infected controls.
methodsA retrospective study was performed with 316 patients (204 RT-PCR positive; 112 RT-PCR negative and chest CT negative). Steatosis was measured with placement of a single ROI in the right lobe of the liver (segments VI-VII) and defined as a liver attenuation value ≤ 40 HU.
resultsThe frequency of hepatic steatosis was higher in the RT-PCR positive group in comparison to controls (31.9% vs. 7.1%, p < 0.001). Logistic linear regression analysis showed a 4.7 times odds of steatosis in the COVID-19 positive group as compared to controls after adjusting for age and sex (OR 4.698; 95% IC 2.12-10.41, p < 0.001).
conclusionA significantly higher prevalence of steatosis was found among COVID-19 positive individuals. These findings are in accordance with other recent studies linking obesity and COVID-19 infection, as there is an intricate relationship between liver steatosis, metabolic syndrome and obesity. Further studies are required to confirm if such association remains after accounting for multiple variables, as well as possible relationships with disease severity and worst clinical outcomes.
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