Evidence map›Paper›PMID 32683600›Full record

ArticleInfectious diseases and therapy2020

Clinical and Molecular Epidemiology of Extended-Spectrum Beta-Lactamase-Producing Escherichia Coli Infections in Metro Detroit: Early Dominance of the ST-131 Clone.

John P Mills, Keith S Kaye, Richard Evans, Elizabeth Salzman, Jason Pogue, Kayoko Hayakawa, Dror Marchaim, Pansy Awasthy, Madiha Salim, Emily T Martin

Open access · goldAbstract read
In one paragraph

Article in Infectious diseases and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Risk Factors for and Mechanisms ofOpen forum infectious diseases · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

John P MillsDepartment of Internal Medicine, Division of Infectious Diseases, University of Michigan Health System, Ann Arbor, MI, USA. millsjo@umich.edu.ORCID http://orcid.org/0000-0001-6529-2911
Keith S KayeDepartment of Internal Medicine, Division of Infectious Diseases, University of Michigan Health System, Ann Arbor, MI, USA.
Richard EvansDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA.
Elizabeth SalzmanDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA.
Jason PogueDepartment of Pharmacy, University of Michigan, Ann Arbor, MI, USA.
Kayoko HayakawaDepartment of Infectious Diseases, Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
Dror MarchaimAssaf Harofeh Medical Center, Zerifin and Sackler School of Medicine, Tel-Aviv University, Tel Aviv, Israel.
Pansy AwasthyDepartment of Pharmacy Services, Sinai-Grace Hospital, Detroit Medical Center, Wayne State University School of Medicine, Detroit, MI, USA.
Madiha SalimDepartment of Medicine, Detroit Medical Center, Wayne State University, Detroit, MI, USA.
Emily T MartinDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA.
University of Michigan · USWayne State University · USNational Center for Global Health and Medicine · JPTel Aviv University · IL

Funding

Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
Optimizing Clinical Use of Polymyxin B: Teaching an Old Drug to Treat SuperbugsR01AI119446 · NIAID · WAYNE STATE UNIVERSITY · PI LI, JIAN, POGUE, JASON MICHAEL · 2015 to 2019
$5.0M
National Institute of Allergy and Infectious Diseases R01-AI119446-01NIAID NIH HHS R01 AI119446NIA NIH HHS P30 AG024824
6 · The paper itself

Abstract

introductionExtended-spectrum beta-lactamase (ESBL)-producing Escherichia coli infections have become endemic worldwide. We aimed to describe the molecular and clinical epidemiology of ESBL-producing E. coli infections during a period of rising global prevalence.

methodsThree hundred sixty-nine consecutive ESBL-producing E. coli infections in Detroit from 2010-2011 were analyzed. Sequence typing (ST) and CH typing were performed. Clinical characteristics and outcomes were compared between patients infected with ST131 and non-ST131 isolates.

resultsNinety-six percent of isolates were ST 131, and 78.6% of ST 131 isolates produced bla

conclusionbla

Indexed as

Escherichia coliExtended spectrum beta-lactamaseSequence typing

Identifiers

PMID32683600
PMCPMC7452991
OpenAlexW3042451178

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.