Evidence map›Paper›PMID 32683417›Full record

Trial reportInternational journal of impotence research2021

Low intensity shockwave therapy in combination with phosphodiesterase-5 inhibitors is an effective and safe treatment option in patients with vasculogenic ED who are PDE5i non-responders: a multicenter single-arm clinical trial.

Alessandro Palmieri, Davide Arcaniolo, Fabrizio Palumbo, Paolo Verze, Giovanni Liguori, Nicola Mondaini, Marco Falcone, Fabrizio Idelfonso Scroppo, Andrea Salonia, Tommaso Cai and 1 more

Abstract readClinical TrialMulticenter Study
PubMed Publisher
In one paragraph

Trial report in International journal of impotence research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 13 institutions in 1 country.

Alessandro PalmieriDepartment of Urology, University Federico II, Naples, Italy.
Davide ArcanioloDepartment of Urology, University Vanvitelli, Naples, Italy.ORCID http://orcid.org/0000-0002-5282-2335
Fabrizio PalumboSan Giacomo Hospital, Monopoli, Bari, Italy.
Paolo VerzeDepartment of Urology, University Federico II, Naples, Italy.
Giovanni LiguoriDepartment of Urology, University of Trieste, Trieste, Italy.ORCID http://orcid.org/0000-0003-2431-5296
Nicola MondainiUrology Unit, Nuovo San Giovanni di Dio Hospital, Florence, Italy.
Marco FalconeDepartment of Urology, University of Turin, Turin, Italy.
Fabrizio Idelfonso ScroppoUrology Unit, Ospedale di Circolo di Varese, Varese, Italy.
Andrea SaloniaDepartment of Urology, University Vita e Salute, San Raffaele, Milan, Italy.
Tommaso CaiDepartment of Urology, Santa Chiara Regional Hospital, Trento, Italy. ktommy@libero.it.ORCID http://orcid.org/0000-0002-7234-3526
SIA-Low intensity shock wave for Erectile Dysfunction (LED) Study Group
Ospedale Santa Chiara · ITUniversity of Campania "Luigi Vanvitelli" · ITCTO Hospital · ITFederico II University Hospital · ITUniversity of Perugia · ITFatebenefratelli Hospital · ITFondazione Audiologica Varese · ITNuovo Ospedale San Giovanni di Dio · ITOspedale San Giacomo Apostolo · ITUniversity of Florence · ITUniversity of Trieste · ITUniversity of Turin · ITVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low-intensity shockwave therapy (Li-ESWT) has been shown to be an effective and safe treatment for vasculogenic erectile dysfunction (ED). We aim to evaluate the effectiveness and safety of LiESWT in treating patients affected from vasculogenic ED who did not respond to oral treatment with Phosphodiesterase 5 inhibitors (PDE5-i). It is a multicentric open-label prospective study, in a cohort of patients non-responders to PDE-5i. Li-ESWT was performed in an outpatient setting by using the following schedule: 3000 shockwaves with an energy of 0.25 mJ/mm

Indexed as

Erectile DysfunctionHigh-Energy Shock WavesCyclic Nucleotide Phosphodiesterases, Type 5HumansMalePenile ErectionPhosphodiesterase 5 InhibitorsProspective StudiesQuality of LifeTreatment OutcomeCyclic Nucleotide Phosphodiesterases, Type 5Phosphodiesterase 5 Inhibitors

Identifiers

PMID32683417
OpenAlexW3042456309

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.