ArticleMedicina oral, patologia oral y cirugia bucal2020
Risk factors related to oral candidiasis in patients with primary Sjögren's syndrome.
Article in Medicina oral, patologia oral y cirugia bucal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 38 citations in OpenAlex.
- Characterization and virulence of yeasts associated with neonatal thrush.BMC microbiology · 2025Article
- In Vitro Evaluation ofInternational journal of molecular sciences · 2025Article
- Clinical features and risk factors for Sjogren's syndrome patients suffering from oral candidiasis in Shanxi, China.BMC oral health · 2024Article
- The experience of dry mouth and screening for Sjogren's syndrome by the dentist: patient-reported experiences.BMC oral health · 2023Article
- [Clinical features of oral management to oral complications of Sjögren's syndrome].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023Article
- Candida albicans stimulates formation of a multi-receptor complex that mediates epithelial cell invasion during oropharyngeal infection.PLoS pathogens · 2023Article
- Article
- High-Throughput Sequencing of Oral Microbiota inJournal of clinical medicine · 2023Article
- Development, optimization, and evaluation of a nanostructured lipid carrier of sesame oil loaded with miconazole for the treatment of oral candidiasis.Drug delivery · 2022Article
- Safety and tolerability of cinnamaldehyde in orabase for oral candidiasis treatment: phase I clinical trial.Clinical oral investigations · 2022Article
- Observational
- Stimulated whole salivary flow rate: The most appropriate technique for assessing salivary flow in Sjögren syndrome.Medicina oral, patologia oral y cirugia bucal · 2021Article
- Review
- Antifungal Activity ofJournal of International Society of Preventive & Community DentistryArticle
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCandidiasis is the most frequent mycotic infection of the oral cavity. The aim of this study was to investigate the presence of clinical oral candidiasis and Candida albicans yeast in a population diagnosed of primary Sjögren's syndrome (pSS) and to study the possible factors associated with this infection. MATERIAL AND
methodsAn observational cross-sectional study was conducted in 61 pSS patients (60 women, 1 man, mean age 57.64±13.52) where patient based information (demographic and medical, tobacco and alcohol consumption history), intraoral parameters (presence of dentures, clinical signs of candidiasis), salivary analytical information (number of Candida albicans as colony-forming units per millilitre (CFU/mL), salivary pH levels, unstimulated whole saliva (UWS) and stimulated whole saliva (SWS) were collected.
results13.1% of pSS patients presented oral signs of candidiasis. Denture stomatitis and angular cheilitis were the most common lesions. 87.5% of patients with clinical candidiasis presented reduced pH levels and salivary flow in both UWS and SWS. A significant statistical negative correlation was found between CFU/mL of Candida albicans and levels of UWS and SWS. A negative correlation was found between pH levels and CFU/mL, although not statistically significant.
conclusionsA reduced salivary flow may predispose pSS patients to Candida albicans overgrowth, which may show with clinical signs. Preventive measures are of great importance to avoid and to treat this condition promptly.
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