Evidence map›Paper›PMID 32682834›Full record

ArticleOphthalmology2021

Evaluation of Metagenomic Deep Sequencing as a Diagnostic Test for Infectious Keratitis.

Prajna Lalitha, N Venkatesh Prajna, Misra Sikha, Rameshkumar Gunasekaran, Armin Hinterwirth, Lee Worden, Cindi Chen, Lina Zhong, Zijun Liu, Thomas M Lietman and 2 more

Abstract readEvaluation Study
In one paragraph

Article in Ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Review
  3. Infectious Keratitis Management: 10-Year Update.Journal of clinical medicine · 2025
    Review
  4. Potential Role ofInternational journal of molecular sciences · 2025
    Article
  5. Article
  6. Article
  7. Etiologies of Infectious Keratitis in Malawi.The American journal of tropical medicine and hygiene · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Journal of clinical medicine · 2023
    Review
  14. Metagenomic sequencing for investigation of a national keratoconjunctivitis outbreak, Israel, 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Article
  15. Article
  16. Modern Technologies in Diagnosis of Fungal Keratitis (Review).Sovremennye tekhnologii v meditsine · 2023
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Prajna LalithaAravind Eye Hospital, Madurai, Tamil Nadu, India.
N Venkatesh PrajnaAravind Eye Hospital, Madurai, Tamil Nadu, India.
Misra SikhaAravind Eye Hospital, Madurai, Tamil Nadu, India.
Rameshkumar GunasekaranAravind Eye Hospital, Madurai, Tamil Nadu, India.
Armin HinterwirthFrancis I. Proctor Foundation, University of California San Francisco, San Francisco, California.
Lee WordenFrancis I. Proctor Foundation, University of California San Francisco, San Francisco, California.
Cindi ChenFrancis I. Proctor Foundation, University of California San Francisco, San Francisco, California.
Lina ZhongFrancis I. Proctor Foundation, University of California San Francisco, San Francisco, California.
Zijun LiuFrancis I. Proctor Foundation, University of California San Francisco, San Francisco, California.
Thomas M LietmanFrancis I. Proctor Foundation, University of California San Francisco, San Francisco, California; Department of Ophthalmology, University of California, San Francisco, California.
Gerami D SeitzmanFrancis I. Proctor Foundation, University of California San Francisco, San Francisco, California; Department of Ophthalmology, University of California, San Francisco, California. Electronic address: seitzman@ucsf.edu.
Thuy DoanFrancis I. Proctor Foundation, University of California San Francisco, San Francisco, California; Department of Ophthalmology, University of California, San Francisco, California.

Funding

Ocular Surface Microbiome, Virome, and Pathogens in Ophthalmic Disease and HealthK08EY026986 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DOAN, THUY A · 2016 to 2020
$1.2M
NEI NIH HHS K08 EY026986
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MetagenomicsCorneal UlcerDiagnostic Tests, RoutineDNA, BacterialEye Infections, BacterialEye Infections, FungalHigh-Throughput Nucleotide SequencingHumansMetagenomeRNA, BacterialStaphylococcal InfectionsStaphylococcusStreptococcal InfectionsStreptococcusDNA, BacterialRNA, Bacterial

Identifiers

PMID32682834
PMCPMC7856230

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.