Trial reportAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2020
Electronic Decision Support for Management of CKD in Primary Care: A Pragmatic Randomized Trial.
Trial report in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02925962 (A Randomized Trial to Evaluate an Electronic CKD Clinical Decision Support System), which is not on this map. Cited by 38 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Trial to Evaluate an Electronic CKD Clinical Decision Support System (CDSS) in Clinical Care
Who cites it
38 citing papers in PubMed, 5 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- Challenges and strategies for managing early-to-moderate chronic kidney disease in primary care: A systematic integrative review in high-income countries.The European journal of general practice · 2026Pooled it
- Pooled it
- Effect of pharmacist interventions in chronic kidney disease: a meta-analysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Pooled it
- The Effectiveness of Pharmacist Interventions in the Management of Patient with Renal Failure: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Decision coaching for people making healthcare decisions.The Cochrane database of systematic reviews · 2021Pooled it
- Clinical Decision Support for Chronic Kidney Disease in Primary Care: A Cluster Randomized Clinical Trial.JAMA network open · 2026Trial
- User Actions within a Clinical Decision Support Alert for the Management of Hypertension in Chronic Kidney Disease.Applied clinical informatics · 2025Trial
- Care Processes and Clinical Responses to Newly Detected Albuminuria: The Stockholm Creatinine Measurements (SCREAM) Project.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2026Article
- A Quasi-Experimental Evaluation of a Primary Care Behavioral Health Integration Program Based on the Chronic Care Model.Journal of general internal medicine · 2026Observational
- Implementation of a Kidney Screening Intervention to Improve Early CKD Detection in Adults with Diabetes.Kidney360 · 2025Article
- The challenges of using electronic medical records (EMR) to facilitate guideline-directed medical therapy (GDMT) for patients with heart failure (HF) and chronic kidney disease (CKD).Heart failure reviews · 2025Review
- Improving CKD Screening and Care in Diabetes Using Clinical Decision Support in a Large Health Care System.Kidney360 · 2025Article
- Health Equity and Artificial Intelligence in Nephrology.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Mind the gap in kidney care: Translating what we know into what we do.Nephrology (Carlton, Vic.) · 2025Article
- Mind the gap in kidney care: translating what we know into what we do.Kidney research and clinical practice · 2025Article
- Article
- Mind the gap in kidney care: translating what we know into what we do.Clinical and experimental nephrology · 2024Review
- Mind the Gap in Kidney Care: Translating What We Know Into What We Do.American journal of hypertension · 2024Article
- Primary care clinician perspectives on automated nephrology e-consults for diabetic kidney disease: a pre-implementation qualitative study.BMC primary care · 2024Article
- Mind the Gap in Kidney Care: Translating What We Know into What We Do.Kidney international reports · 2024Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
RATIONALE &
objectiveMost adults with chronic kidney disease (CKD) in the United States are cared for by primary care providers (PCPs). We evaluated the feasibility and preliminary effectiveness of an electronic clinical decision support system (eCDSS) within the electronic health record with or without pharmacist follow-up to improve the management of CKD in primary care. STUDY
designPragmatic cluster-randomized trial. SETTING &
participants524 adults with confirmed creatinine-based estimated glomerular filtration rates of 30 to 59mL/min/1.73m
interventionsEach PCP's eligible patients were randomly assigned as a group into 1 of 3 treatment arms: (1) usual care; (2) eCDSS: testing of creatinine, cystatin C, and urinary albumin-creatinine ratio with individually tailored guidance for PCPs on blood pressure, potassium, and proteinuria management, cardiovascular risk reduction, and patient education; or (3) eCDSS plus pharmacist counseling (eCDSS-PLUS). OUTCOMES: The primary clinical outcome was change in blood pressure over 12 months. Secondary outcomes were PCP awareness of CKD and use of angiotensin-converting enzyme inhibitor/angiotensin receptor blocker and statin therapy.
resultsAll 80 eligible PCPs participated. Mean patient age was 70 years, 47% were nonwhite, and mean estimated glomerular filtration rate was 56±0.6mL/min/1.73m LIMITATIONS: Recruitment of smaller than intended sample size and limited uptake of the testing component of the intervention.
conclusionsAlthough we were unable to demonstrate the effectiveness of eCDSS to lower blood pressure and uptake of the eCDSS was limited by low testing rates, eCDSS use was high when laboratory measurements were available and was associated with higher PCP awareness of CKD.
fundingGrants from government (National Institutes of Health) and not-for-profit (American Heart Association) entities.
trial registrationRegistered at ClinicalTrials.gov with study number NCT02925962.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.