Evidence map›Paper›PMID 32682613›Full record

ArticleExperimental neurology2020

An automated pressure-swing absorption system to administer low oxygen therapy for persons with spinal cord injury.

A Q Tan, J M Papadopoulos, A N Corsten, R D Trumbower

2 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Experimental neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02632422 naactive not recruitingnot on this map

Intermittent Hypoxia-Induced Recovery of Overground Walking in Persons With Subacute SCI

TypeinterventionalSponsorSpaulding Rehabilitation HospitalRan2015 to 2027Enrolled125ConditionsSpinal Cord InjuryArmsDaily acute intermittent hypoxia (dAIH), dSHAM, Walking
NCT05217498 phase1 / phase2not yet recruitingnot on this mapstarted 2027, after this paper: background citation

A Selective Adenosine 2a Antagonist to Enhance Training-related Gains in Walking Function for Persons With Chronic, Incomplete Spinal Cord Injury

TypeinterventionalSponsorRandy Trumbower, PT, PhDRan2027 to 2028Enrolled40ConditionsSpinal Cord Injuries, MyelopathyArmsIstradefylline, low oxygen therapy
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

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  5. Author response to Panza et al.The Journal of physiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

A Q TanDepartment of Physical Medicine & Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, 1575 Cambridge Street, MA 02138, USA; Spaulding Research Institute, Spaulding Rehabilitation Hospital, 1575 Cambridge Street, Boston, MA 02138, USA.
J M PapadopoulosSpaulding Research Institute, Spaulding Rehabilitation Hospital, 1575 Cambridge Street, Boston, MA 02138, USA.
A N CorstenSpaulding Research Institute, Spaulding Rehabilitation Hospital, 1575 Cambridge Street, Boston, MA 02138, USA.
R D TrumbowerDepartment of Physical Medicine & Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, 1575 Cambridge Street, MA 02138, USA; Spaulding Research Institute, Spaulding Rehabilitation Hospital, 1575 Cambridge Street, Boston, MA 02138, USA. Electronic address: randy.trumbower@mgh.harvard.edu.
Harvard University · USSpaulding Rehabilitation Hospital · US

Funding

Mechanisms of intermittent hypoxia-induced motor recovery in persons with SCIR01HD081274 · NICHD · SPAULDING REHABILITATION HOSPITAL · PI TRUMBOWER, RANDY D · 2014 to 2018
$2.4M
NICHD NIH HHS R01 HD081274
6 · The paper itself

Abstract

Mild episodes of breathing low oxygen (O

Indexed as

AutomationBlood PressureDrug Delivery SystemsFeedback, SensoryFemaleHealthy VolunteersHeart RateHumansMaleOxygenOxygen Inhalation TherapyRecovery of FunctionReproducibility of ResultsSpinal Cord InjuriesTemperatureOxygenBreathingHypoxiaMotor functionOxygenPressure swing adsorptionRehabilitationSpinal cord injury

Identifiers

PMID32682613
PMCPMC7502479
OpenAlexW3042257182

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.