Evidence map›Paper›PMID 32682559›Full record

Trial reportBritish journal of anaesthesia2020

Individualized PEEP to optimise respiratory mechanics during abdominal surgery: a pilot randomised controlled trial.

Ana Fernandez-Bustamante, Juraj Sprung, Robert A Parker, Karsten Bartels, Toby N Weingarten, Carolina Kosour, B Taylor Thompson, Marcos F Vidal Melo

4 registry-linked trialsOpen access · greenAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in British journal of anaesthesia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 48 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 5 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02671721 nacompletednot on this map

Intraoperative Protective Ventilation and Postoperative Pulmonary Complications

TypeinterventionalSponsorMassachusetts General HospitalRan2016 to 2017Enrolled40ConditionsComplication of Ventilation Therapy, Postoperative Respiratory ComplicationsArmsMaximal Compliance, Transpulmonary Pressure
NCT06150079 nacompletednot on this mapstarted 2023, after this paper: background citation

Effect of Individualized PEEP Titration on Postoperative Pulmonary Complications in Elderly Patients Undergoing Major Laparoscopic Surgery- A Multicenter Randomized Controlled Clinical Trial

TypeinterventionalSponsorShanghai Zhongshan HospitalRan2023 to 2025Enrolled240ConditionsPostoperative Pulmonary Complications, Positive End-expiratory Pressure, Elderly, Laparoscopic SurgeryArmsPes-Guided PEEP titration
NCT06929078 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Role of Individualized Positive End-expiratory Pressure Versus Fixed Positive End-expiratory Pressure in Mechanical Ventilation During Laparoscopic Surgeries

TypeinterventionalSponsorNoor-Ul-AinRan2025 to 2025Enrolled75ConditionsLaparoscopic Surgery, Pneumoperitoneum, Positive End Expiratory Pressure (PEEP)ArmsProtective lung ventilation methods with different positive end-expiratory pressure during Laparoscopic Surgeries
NCT07728214 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Reminder-enhanced Incentive Spirometry Evaluation (RISE)

TypeinterventionalSponsorUniversity of Colorado, DenverRan2026 to 2029Enrolled88ConditionsHypoxemiaArmsAlarms ON
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 5 syntheses or guidelines pooled it, 69 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Ana Fernandez-BustamanteDepartment of Anesthesiology, University of Colorado School of Medicine, Aurora, CO, USA; Webb-Waring Center, University of Colorado School of Medicine, Aurora, CO, USA. Electronic address: Ana.Fernandez-Bustamante@cuanschutz.edu.
Juraj SprungDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA.
Robert A ParkerDepartment of Medicine, Biostatistics Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Karsten BartelsDepartment of Anesthesiology, University of Colorado School of Medicine, Aurora, CO, USA.
Toby N WeingartenDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA.
Carolina KosourDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
B Taylor ThompsonDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Marcos F Vidal MeloDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Harvard University · USMayo Clinic in Arizona · USUniversity of Colorado Denver · USMassachusetts General Hospital · US

Funding

1/2: An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR StudyUH3HL140177 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI FERNANDEZ-BUSTAMANTE, ANA, VIDAL MELO, MARCOS F · 2020 to 2023
$6.6M
1/2: An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR StudyUG3HL140177 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI FERNANDEZ-BUSTAMANTE, ANA, VIDAL MELO, MARCOS F · 2019 to 2019
$1.2M
Intraoperative Protective Ventilation and Postoperative Pulmonary ComplicationsR34HL123438 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI VIDAL MELO, MARCOS F · 2015 to 2017
$599k
NHLBI NIH HHS R34 HL123438NHLBI NIH HHS UG3 HL140177NHLBI NIH HHS UH3 HL140177
6 · The paper itself

Abstract

backgroundHigher intraoperative driving pressures (ΔP) are associated with increased postoperative pulmonary complications (PPC). We hypothesised that dynamic adjustment of PEEP throughout abdominal surgery reduces ΔP, maintains positive end-expiratory transpulmonary pressures (P

methodsIn a prospective multicentre pilot study, adults at moderate/high risk for PPC undergoing elective abdominal surgery were randomised to one of three ventilation protocols: (1) PEEP≤2 cm H

resultsThirty-seven patients (48.6% female; age range: 47-73 yr) were assigned to control (PEEP≤2 cm H

conclusionsThis pilot study suggests that individualised PEEP management strategies applied during abdominal surgery reduce driving pressure, maintain positive P CLINICAL

trial registrationNCT02671721.

Indexed as

AbdomenAgedFeasibility StudiesFemaleHumansIntraoperative CareMaleMiddle AgedPilot ProjectsPositive-Pressure RespirationPostoperative ComplicationsProspective StudiesRespiratory Mechanicslung compliancemechanical ventilationpositive end-expiratory pressurepostoperative pulmonary complicationsrespiratory mechanicsventilator-induced lung injury

Identifiers

PMID32682559
PMCPMC7497030
OpenAlexW3042419176

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.