Evidence map›Paper›PMID 32682454›Full record

ReviewThe American journal of tropical medicine and hygiene2020

SARS-CoV-2: Should We Be Concerned about the Nervous System?

Marcus Tulius T Silva, Marco Lima, Abelardo Q-C Araujo

Open access · bronzeAbstract readReview
In one paragraph

Review in The American journal of tropical medicine and hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Marcus Tulius T Silva1Brazilian Ministry of Health, Evandro Chagas National Institute of Infectious Diseases (INI), Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Marco Lima1Brazilian Ministry of Health, Evandro Chagas National Institute of Infectious Diseases (INI), Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Abelardo Q-C Araujo1Brazilian Ministry of Health, Evandro Chagas National Institute of Infectious Diseases (INI), Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Fundação Oswaldo Cruz · BRMinistério da Saúde · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic has proved to be an enormous challenge to the health of the world population with tremendous consequences for the world economy. New knowledge about COVID-19 is being acquired continuously. Although the main manifestation of COVID-19 is SARS, dysfunction in other organs has been described in the last months. Neurological aspects of COVID-19 are still an underreported subject. However, a plethora of previous studies has shown that human CoVs might be neurotropic, neuroinvasive, and neurovirulent, highlighting the importance of this knowledge by physicians. Besides, several neurological manifestations had been described as complications of two other previous outbreaks of CoV diseases (SARS ad Middle East respiratory syndrome). Therefore, we should be watchful, searching for early evidence of neurological insults and promoting clinical protocols to investigate them. Our objectives are to review the potential neuropathogenesis of this new CoV and the neurological profile of COVID-19 patients described so far.

Indexed as

BetacoronavirusCoronavirus InfectionsCOVID-19HumansNervous System DiseasesPandemicsPneumonia, ViralSARS-CoV-2

Identifiers

PMID32682454
PMCPMC7470530
OpenAlexW3043641384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.