Evidence map›Paper›PMID 32682442›Full record

ArticleSystematic reviews2020

Combining abbreviated literature searches with single-reviewer screening: three case studies of rapid reviews.

Lisa Affengruber, Gernot Wagner, Siw Waffenschmidt, Stefan K Lhachimi, Barbara Nussbaumer-Streit, Kylie Thaler, Ursula Griebler, Irma Klerings, Gerald Gartlehner

Abstract read
In one paragraph

Article in Systematic reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lisa AffengruberDepartment for Evidence-based Medicine and Evaluation, Cochrane Austria, Danube University Krems, Dr. Karl Dorrek Strasse 30, 3500, Krems, Austria. lisa.affengruber@donau-uni.ac.at.ORCID 0000-0002-7721-8732
Gernot WagnerDepartment for Evidence-based Medicine and Evaluation, Cochrane Austria, Danube University Krems, Dr. Karl Dorrek Strasse 30, 3500, Krems, Austria.
Siw WaffenschmidtInformation Management Unit, Institute for Quality and Efficiency in Health Care (IQWiG), Im Mediapark 8, 50670, Cologne, Germany.
Stefan K LhachimiResearch Group Evidence-Based Public Health, Leibniz Institute for Epidemiology and Prevention Research (BIPS), Bremen, Germany.
Barbara Nussbaumer-StreitDepartment for Evidence-based Medicine and Evaluation, Cochrane Austria, Danube University Krems, Dr. Karl Dorrek Strasse 30, 3500, Krems, Austria.
Kylie ThalerMedical Department I, Hanusch Krankenhaus der Wiener Gebietskrankenkasse, Heinrich-Collin-Straße 30, 1140, Vienna, Austria.
Ursula GrieblerDepartment for Evidence-based Medicine and Evaluation, Cochrane Austria, Danube University Krems, Dr. Karl Dorrek Strasse 30, 3500, Krems, Austria.
Irma KleringsDepartment for Evidence-based Medicine and Evaluation, Cochrane Austria, Danube University Krems, Dr. Karl Dorrek Strasse 30, 3500, Krems, Austria.
Gerald GartlehnerDepartment for Evidence-based Medicine and Evaluation, Cochrane Austria, Danube University Krems, Dr. Karl Dorrek Strasse 30, 3500, Krems, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDecision-makers increasingly request rapid answers to clinical or public health questions. To save time, personnel, and financial resources, rapid reviews streamline the methodological steps of the systematic review process. We aimed to explore the validity of a rapid review approach that combines a substantially abbreviated literature search with a single-reviewer screening of abstracts and full texts using three case studies.

methodsWe used a convenience sample of three ongoing Cochrane reviews as reference standards. Two reviews addressed oncological topics and one addressed a public health topic. For each of the three topics, three reviewers screened the literature independently. Our primary outcome was the change in conclusions between the rapid reviews and the respective Cochrane reviews. In case the rapid approach missed studies, we recalculated the meta-analyses for the main outcomes and asked Cochrane review authors if the new body of evidence would change their original conclusion compared with the reference standards. Additionally, we assessed the sensitivity of the rapid review approach compared with the results of the original Cochrane reviews.

resultsFor the two oncological topics (case studies 1 and 2), the three rapid reviews each yielded the same conclusions as the Cochrane reviews. However, the authors would have had less certainty about their conclusion in case study 2. For case study 3, the public health topic, only one of the three rapid reviews led to the same conclusion as the Cochrane review. The other two rapid reviews provided insufficient information for the authors to draw conclusions. Using the rapid review approach, the sensitivity was 100% (3 of 3) for case study 1. For case study 2, the three rapid reviews identified 40% (4 of 10), 50% (5 of 10), and 60% (6 of 10) of the included studies, respectively; for case study 3, the respective numbers were 38% (8 of 21), 43% (9 of 21), and 48% (10 of 21).

conclusionsWithin the limitations of these case studies, a rapid review approach that combines abbreviated literature searches with single-reviewer screening may be feasible for focused clinical questions. For complex public health topics, sensitivity seems to be insufficient.

Indexed as

PublicationsResearch DesignHumansReview Literature as TopicEvidence synthesisHealth care decision-makingRapid reviewSystematic review

Identifiers

PMID32682442
PMCPMC7368980

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.