ArticlePlant molecular biology2020
Arabidopsis FAX1 mediated fatty acid export is required for the transcriptional regulation of anther development and pollen wall formation.
Article in Plant molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 47 citations in OpenAlex.
- Transcriptome analysis of a spontaneous male-sterile mutant in Betula platyphylla and functional characterization of the key gene BpSPL2 in regulating inflorescence development.Plant cell reports · 2026Article
- Genome-Wide Identification and Analysis of the Fatty Acid Export Family Revealed the Role ofPlants (Basel, Switzerland) · 2025Article
- Gene expression profiles and metabolic pathways responsible for male sterility in cybrid pummelo.Plant cell reports · 2024Article
- FatPlants: a comprehensive information system for lipid-related genes and metabolic pathways in plants.Database : the journal of biological databases and curation · 2024Article
- Degradation of FATTY ACID EXPORT PROTEIN1 by RHOMBOID-LIKE PROTEASE11 contributes to cold tolerance in Arabidopsis.The Plant cell · 2024Article
- The transcription factors and pathways underpinning male reproductive development in Arabidopsis.Frontiers in plant science · 2024Review
- The haplotype-resolved autotetraploid genome assembly provides insights into the genomic evolution and fruit divergence in wax apple (Horticulture research · 2023Article
- ROS accumulation-induced tapetal PCD timing changes leads to microspore abortion in cotton CMS lines.BMC plant biology · 2023Article
- Ascorbic acid-mediated reactive oxygen species homeostasis modulates the switch from tapetal cell division to cell differentiation in Arabidopsis.The Plant cell · 2023Article
- Fatty acid exporter 1 enhances seed oil content inMolecular breeding : new strategies in plant improvement · 2022Article
- Transcriptome profiling of flower buds of male-sterile lines provides new insights into male sterility mechanism in alfalfa.BMC plant biology · 2022Article
- Functions of Redox Signaling in Pollen Development and Stress Response.Antioxidants (Basel, Switzerland) · 2022Review
- Homology-based identification of candidate genes for male sterility editing in upland cotton (Frontiers in plant science · 2022Review
- Fatty acid export (FAX) proteins contribute to oil production in the green microalgaFrontiers in molecular biosciences · 2022Article
- Potential Association of Reactive Oxygen Species With Male Sterility in Peach.Frontiers in plant science · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
key messageThe mutation of FAX1 (Fatty Acid Export 1) disrupts ROS homeostasis and suppresses transcription activity of DYT1-TDF1-AMS-MS188 genetic network, leading to atypical tapetum PCD and defective pollen formation in Arabidopsis. Fatty acids (FAs) have multiple important biological functions and exert diverse cellular effects through modulating Reactive Oxygen Species (ROS) homeostasis. Arabidopsis FAX1 (Fatty Acid Export 1) mediates the export of de novo synthesized FA from chloroplast and loss of function of FAX1 impairs male fertility. However, mechanisms underlying the association of FAX1-mediated FA export with male sterility remain enigmatic. In this study, by using an integrated approach that included morphological, cytological, histological, and molecular analyses, we revealed that loss of function of FAX1 breaks cellular FA/lipid homeostasis, which disrupts ROS homeostasis and suppresses transcriptional activation of the DYT1-TDF1-AMS-MS188 genetic network of anther development, impairing tapetum development and pollen wall formation, and resulting in male sterility. This study provides new insights into the regulatory network for male reproduction in plants, highlighting an important role of FA export-mediated ROS homeostasis in the process.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.