SynthesisInternational urogynecology journal2020
Percutaneous tibial nerve stimulation for overactive bladder syndrome: a systematic review and meta-analysis.
Synthesis in International urogynecology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Sacral and Implantable Tibial Neuromodulation for the Management of Overactive Bladder: A Systematic Review and Meta-analysis.Advances in therapy · 2025Pooled it
- Evidence evaluation of acupuncture and its related therapies for female urinary incontinence: an overview and quality assessment of systematic reviews and meta-analyses.European journal of physical and rehabilitation medicine · 2024Pooled it
- The effectiveness of different electrical nerve stimulation protocols for treating adults with non-neurogenic overactive bladder: a systematic review and meta-analysis.International urogynecology journal · 2022Pooled it
- Randomized trial of unilateral versus bilateral percutaneous tibial nerve stimulation for the treatment of overactive bladder.World journal of urology · 2025Trial
- Comparison of transcutaneous electrical tibial nerve stimulation for the treatment of overactive bladder: a multi-arm randomized controlled trial with blinded assessment.Clinics (Sao Paulo, Brazil) · 2021Trial
- Sacral Neuromodulation for Refractory Overactive Bladder: Closing the Gaps in Anatomy, Mechanisms, and Parameter Selection.Advances in therapy · 2026Review
- Neuromodulation for Lower Urinary Tract Dysfunction: Mechanisms, Modalities, and Patient Selection.International urogynecology journal · 2026Review
- Chemodenervation Use for Overactive Bladder in Female Medicare Beneficiaries.Urogynecology (Philadelphia, Pa.) · 2026Article
- Tibial Nerve Stimulation: Recent Progress and Challenges.Current urology reports · 2026Review
- Wireless electrostimulation implants enable sphincter neuromuscular improvement toward mixed urinary incontinence.Nature communications · 2026Article
- Tibial nerve stimulation for overactive bladder: a literature review of stimulation parameters.Translational andrology and urology · 2026Review
- Impact of Weekly Application Frequency on the Efficacy of Tibial Nerve Stimulation Therapy in the Treatment of Overactive Bladder.International urogynecology journal · 2026Article
- Remote neurodegeneration in the lumbosacral cord one month after spinal cord injury: a cross-sectional MRI study.Annals of clinical and translational neurology · 2025Article
- Posterior Tibial Nerve Stimulation for the Treatment of Detrusor Overactivity in Multiple Sclerosis Patients: A Narrative Review.Journal of personalized medicine · 2024Review
- Machine learning enables non-Gaussian investigation of changes to peripheral nerves related to electrical stimulation.Scientific reports · 2024Article
- Efficacy and sex-specific outcomes after six episodes of percutaneous tibial nerve stimulation treatment on overactive bladder syndrome symptoms.Frontiers in urology · 2024Article
- Percutaneous Tibial Nerve Stimulation in the Treatment of Refractory Idiopathic Overactive Bladder Syndrome: A Retrospective Cohort Study.Journal of clinical medicine · 2023Article
- Development of a Sham Protocol to Investigate Transcutaneous Tibial Nerve Stimulation in Randomised, Sham-Controlled, Double-Blind Clinical Trials.Biomedicines · 2023Article
- Peroneal electrical transcutaneous neuromodulation in the home treatment of the refractory overactive bladder.International urogynecology journal · 2023Article
- The Investigation of Percutaneous Tibial Nerve Stimulation (PTNS) as a Minimally Invasive, Non-Surgical, Non-Hormonal Treatment for Overactive Bladder Symptoms.Journal of clinical medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
introduction and hypothesisThis systematic review and meta-analysis aimed to evaluate the efficacy and safety of percutaneous tibial nerve stimulation (PTNS) for the treatment of overactive bladder (OAB) syndrome.
methodsPubMed, Embase, Web of Science and Cochrane Library were searched systematically to identify all the relevant studies. Void frequency per day, nocturia frequency per day, urgency episodes per day, incontinence episodes per day, urodynamic values, success rate and side effects, etc., were extracted from the included studies and analyzed.
resultsTwenty-eight studies with 2461 patients in total were included. Results showed that there was a significant clinical effect on the voiding frequency per day (MD = -2.48; 95% CI -3.19, -1.76; P < 0.001), nocturia frequency per day (MD = -1.57; 95% CI -2.16, -0.99; P < 0.001), urgency episodes per day (MD = -2.20; 95% CI -3.77, -0.62; P = 0.006), incontinence episodes per day (MD = -1.37; 95% CI -1.71, -1.02; P < 0.001), maximum cystometric capacity (MD = 63.76; 95% CI 31.90, 95.61; P < 0.001) and compliance (MD = 7.62; 95% CI 0.61, 14.63; P = 0.033). The pooled success rate was 0.68 (95% CI 0.59, 0.78). The major complication was the pain at the puncture site, but the incidence was low.
conclusionsPTNS is effective and safe in treating OAB symptoms.
Indexed as
Identifiers
32681345What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.