SynthesisWorld journal of surgery2020
Global Gender Differences in Pilonidal Sinus Disease: A Random-Effects Meta-Analysis.
Synthesis in World journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Karydakis Flap Procedure Versus Burow's Triangle Advancement Flap Procedure in the Surgical Treatment of Sacrococcygeal Pilonidal Sinus Disease
Examining the Effect of Additional Injection of Freshly Collected Autologous Adipose Tissue to Bascom's Cleft Lift Surgery in the Treatment of Pilonidal Disease- a Randomized Controlled Trial
Who cites it
18 citing papers in PubMed, 44 citations in OpenAlex.
- Excision and suture in the midline versus Karydakis flap surgery for pilonidal sinus: randomized clinical trial.BJS open · 2022Trial
- Karydakis Versus Limberg Flap in Primary Sacrococcygeal Pilonidal Sinus: A Retrospective Comparative Study of Functional Recovery.World journal of surgery · 2026Observational
- Five-year trends in proctological practice in Dubai: Insights from a high-volume referral centre.BMC surgery · 2026Article
- Pilonidal pit fibroblasts release cytokines that differ by sex and are altered by estrogen.Pediatric surgery international · 2026Article
- A promising novel material-light-cured wound closure adhesives promote wound healing after pilonidal sinus open surgery: a Case Report.Frontiers in bioengineering and biotechnology · 2025Article
- Pediatric pilonidal sinus disease: Recurrence rates of different age groups compared to adults.Surgery open science · 2025Article
- Evaluation of phenol treatment for pilonidal sinus in adolescents.Frontiers in pediatrics · 2025Article
- Time trends in incidence of pilonidal sinus disease from 1996 to 2021: A Danish population-based cohort study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2024Article
- Closed-incision negative-pressure wound therapy after Bascom's cleft lift surgery for pilonidal sinus disease: A randomized study comparing healing.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2024Article
- Long-term outcomes after cleft lift surgery for pilonidal sinus disease in post-pubertal adolescents: data from a prospective Danish cohort.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2024Article
- Demographic overview of pilonidal sinus carcinoma: updated insights into the incidence.International journal of colorectal disease · 2023Article
- Evaluation of the coexistence of pilonidal sinus disease and hirsutism in female patients: a retrospective cross-sectional study.Annals of medicine and surgery (2012) · 2023Article
- Use of the laser in the pilonidal sinus alone or in combination with phenol.Revista da Associacao Medica Brasileira (1992) · 2023Article
- Article
- Review
- Pit picking vs. Limberg flap vs. primary open method to treat pilonidal sinus disease - A cohort of 327 consecutive patients.Innovative surgical sciences · 2022Article
- Pilonidal sinus disease on the rise: a one-third incidence increase in inpatients in 13 years with substantial regional variation in Germany.International journal of colorectal disease · 2021Article
- Primary Transverse Closure Compared to Open Wound Treatment for Primary Pilonidal Sinus Disease in Children.Children (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPilonidal sinus disease (PSD) is traditionally associated with young male patients. While PSD is rare in Asia and Africa, lifestyles are changing considerably throughout the so-called developed world. We question that PSD is an overwhelmingly male disease and that the proportion of women suffering from PSD is worldwide evenly distributed in a homogenous matter.
methodsWe analysed the world literature published between 1833 and 2018, expanding on the database created by Stauffer et al. Following correction for gender bias with elimination of men-only and women-only studies, data were processed using random-effects meta-analysis in the technique of DerSimonian and Laird.
resultsThe share of female pilonidal sinus disease patients analysed from all studies available in the world literature is 21%. There are marked regional differences including South America (39%), North America as well as Australia/New Zealand (29%) and Asia (7%), which are highly significant. These results stand fast even if analysis without gender bias corrections was applied.
conclusionThe share of female patients suffering from PSD is considerable. It is time to think of PSD as a disease of both men and women. Previously unknown, there are significant regional differences worldwide; the reason(s) for the regional differences is still unclear.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.