ArticleCognitive, affective & behavioral neuroscience2020
Amygdalostriatal coupling underpins positive but not negative coloring of ambiguous affect.
Article in Cognitive, affective & behavioral neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Corticostriatal responses to social reward are linked to trait reward sensitivity and subclinical substance use in young adults.Social cognitive and affective neuroscience · 2024Article
- Corticostriatal Responses to Social Reward are Linked to Trait Reward Sensitivity and Subclinical Substance Use in Young Adults.bioRxiv : the preprint server for biology · 2024Article
- Interoception Primes Emotional Processing: Multimodal Evidence from Neurodegeneration.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Dopaminergic Regulation of Reward System Connectivity Underpins Pain and Emotional Suffering in Migraine.Journal of pain research · 2021Article
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Authors and funding
3 authors at 3 institutions in 2 countries.
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Abstract
Humans routinely integrate affective information from multiple sources. For example, we rarely interpret an emotional facial expression devoid of context. In this paper, we describe the neural correlates of an affective computation that involves integrating multiple sources, by leveraging the ambiguity and subtle feature-based valence signals found in surprised faces. Using functional magnetic resonance imaging, participants reported the valence of surprised faces modulated by positive or negative sentences. Amygdala activity corresponded to the valence value assigned to each contextually modulated face, with greater activity reflecting more negative ratings. Amygdala activity did not track the valence of the faces or sentences per se. Moreover, the amygdala was functionally coupled with the nucleus accumbens only during face trials preceded by positive contextual cues. These data suggest 1) valence-related amygdala activity reflects the integrated valence values rather than the valence values of each individual component, and 2) amygdalostriatal coupling underpins positive but not negative coloring of ambiguous affect.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.