Evidence map›Paper›PMID 32681249›Full record

ReviewCurrent medical science2020

Vascular Metabolic Mechanisms of Pulmonary Hypertension.

Xiao-Fan Shi, Yun-Chao Su

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Xiao-Fan ShiDepartment of Pharmacology & Toxicology, Augusta University, Augusta, GA, 30912, USA.
Yun-Chao SuDepartment of Pharmacology & Toxicology, Augusta University, Augusta, GA, 30912, USA. ysu@augusta.edu.
Augusta University · US

Funding

PFKFB3 in vascular remodelingR01HL134934 · NHLBI · AUGUSTA UNIVERSITY · PI HUO, YUQING, SU, YUNCHAO · 2017 to 2020
$2.3M
6 · The paper itself

Abstract

Pulmonary hypertension (PH) is a severe and progressive disease characterized by increased pulmonary vascular resistance leading to right heart failure and death. In PH, the cellular metabolisms including those of the three major nutrients (carbohydrate, lipid and protein) are aberrant in pulmonary vascular cells. Glucose uptake, glycolysis, insulin resistance, sphingolipid S1P, PGE

Indexed as

AnimalsCell ProliferationEndothelial CellsHumansHydrogen-Ion ConcentrationHypertension, PulmonaryLungMyocytes, Smooth MuscleSignal TransductionVascular Remodelingmetabolismproliferationpulmonary hypertensionvascular remodeling

Identifiers

PMID32681249
OpenAlexW3043190438

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.