Evidence map›Paper›PMID 32681138›Full record

ArticleScientific reports2020

Low-frequency oscillations reflect aberrant tone restoration during the auditory continuity illusion in schizophrenia.

Joseph Wooldridge, Mathis Kaiser, Yadira Roa Romero, Lars Riecke, Julian Keil, Daniel Senkowski

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Joseph WooldridgeDepartment of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, St. Hedwig Hospital, Große Hamburger Str. 5-11, 10115, Berlin, Germany. joseph.d.wooldridge@gmail.com.
Mathis KaiserDepartment of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, St. Hedwig Hospital, Große Hamburger Str. 5-11, 10115, Berlin, Germany.
Yadira Roa RomeroDepartment of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, St. Hedwig Hospital, Große Hamburger Str. 5-11, 10115, Berlin, Germany.
Lars RieckeDepartment of Cognitive Neuroscience, Maastricht University, Maastricht, The Netherlands.
Julian KeilDepartment of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, St. Hedwig Hospital, Große Hamburger Str. 5-11, 10115, Berlin, Germany.
Daniel SenkowskiDepartment of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, St. Hedwig Hospital, Große Hamburger Str. 5-11, 10115, Berlin, Germany.
Charité - Universitätsmedizin Berlin · DEKiel University · DEMaastricht University · NL

Funding

European Research Council ERC-2010-StG-20091209
6 · The paper itself

Abstract

Patients with schizophrenia (ScZ) often show impairments in auditory information processing. These impairments have been related to clinical symptoms, such as auditory hallucinations. Some researchers have hypothesized that aberrant low-frequency oscillations contribute to auditory information processing deficits in ScZ. A paradigm for which modulations in low-frequency oscillations are consistently found in healthy individuals is the auditory continuity illusion (ACI), in which restoration processes lead to a perceptual grouping of tone fragments and a mask, so that a physically interrupted sound is perceived as continuous. We used the ACI paradigm to test the hypothesis that low-frequency oscillations play a role in aberrant auditory information processing in patients with ScZ (N = 23). Compared with healthy control participants we found that patients with ScZ show elevated continuity illusions of interrupted, partially-masked tones. Electroencephalography data demonstrate that this elevated continuity perception is reflected by diminished 3 Hz power. This suggests that reduced low-frequency oscillations relate to elevated restoration processes in ScZ. Our findings support the hypothesis that aberrant low-frequency oscillations contribute to altered perception-related auditory information processing in ScZ.

Indexed as

HallucinationsSchizophrenic PsychologyAcoustic StimulationData AnalysisElectroencephalographyEvoked Potentials, AuditoryFemaleHumansIllusionsMaleSchizophrenia

Identifiers

PMID32681138
PMCPMC7367839
OpenAlexW3043721075

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.