Evidence map›Paper›PMID 32681124›Full record

Trial reportScientific reports2020

Reliability and suitability of physiological exercise response and recovery markers.

Thomas Reichel, Tim K Boßlau, Jana Palmowski, Klaus Eder, Robert Ringseis, Frank C Mooren, Rüdiger Walscheid, Evita Bothur, Stefan Samel, Torsten Frech and 2 more

Abstract readClinical Trial
In one paragraph

Trial report in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Thomas ReichelInstitute of Sports Science, Department of Exercise and Health, Leibniz University Hanover, 30167, Hannover, Germany.
Tim K BoßlauInstitute of Sports Science, Department of Exercise and Health, Leibniz University Hanover, 30167, Hannover, Germany.
Jana PalmowskiDepartment of Exercise Physiology and Sports Therapy, Institute of Sports Science, Justus-Liebig-University Giessen, Kugelberg 62, 35394, Giessen, Germany.
Klaus EderInstitute of Animal Nutrition and Nutrition Physiology, Justus-Liebig-University Giessen, 35394, Giessen, Germany.
Robert RingseisInstitute of Animal Nutrition and Nutrition Physiology, Justus-Liebig-University Giessen, 35394, Giessen, Germany.
Frank C MoorenDepartment of Rehabilitation, Faculty of Health, Witten/Herdecke University, 58455, Witten, Germany.
Rüdiger WalscheidMedical Center for Laboratory Medicine and Microbiology, Koblenz-Mittelrhein, 56068, Koblenz, Germany.
Evita BothurMedical Center for Laboratory Medicine and Microbiology, Koblenz-Mittelrhein, 56068, Koblenz, Germany.
Stefan SamelMedical Center for Laboratory Medicine and Microbiology, Koblenz-Mittelrhein, 56068, Koblenz, Germany.
Torsten FrechDepartment of Exercise Physiology and Sports Therapy, Institute of Sports Science, Justus-Liebig-University Giessen, Kugelberg 62, 35394, Giessen, Germany.
Marc PhilippeDepartment of Exercise Physiology and Sports Therapy, Institute of Sports Science, Justus-Liebig-University Giessen, Kugelberg 62, 35394, Giessen, Germany.
Karsten KrügerDepartment of Exercise Physiology and Sports Therapy, Institute of Sports Science, Justus-Liebig-University Giessen, Kugelberg 62, 35394, Giessen, Germany. Karsten.Krueger@sport.uni-giessen.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is currently insufficient evidence about the reliable quantification of exercise load and athlete's recovery management for monitoring training processes. Therefore, this test-retest study investigated the reliability of various subjective, muscle force, and blood-based parameters in order to evaluate their suitability for monitoring exercise and recovery cycles. 62 subjects completed two identical 60-min continuous endurance exercise bouts intermitted by a four-week recovery period. Before, immediately after, three, and 24 h after each exercise bout, analysis of parameters were performed. Significant changes over time were found for rating of perceived exertion (RPE), multidimensional mood state questionnaire (MDMQ), maximum voluntary contraction parameters (MVCs), and blood-based biomarkers (p < 0.05). Excellent reliability was calculated for MVCs, mean corpuscular volume and 5-bound distance (ICC > 0.90). A good reliability was found for thiobarbituric acid reactive substances (TBARS) (ICC = 0.79) and haematological markers (ICC = 0.75-0.86). For RPE, MDMQ, interleukin (IL-) 1RA, IL-6, IL-8, IL-15, cortisol, lactate dehydrogenase (LDH), creatine kinase (CK) only moderate reliability was found (ICC < 0.75). Significant associations for IL1-RA and CK to MVC were found. The excellent to moderate reliability of TBARS, LDH, IL-1RA, six measured haematological markers, MVCs and MDMQ implicate their suitability as physiological exercise response and recovery markers for monitoring athletes' load management.

Indexed as

AdultBiomarkersBiomechanical PhenomenaBlood ProteinsCytokinesEnzymesExerciseFemaleHormonesHumansMaleMetabolomeMusclesReproducibility of ResultsYoung AdultBiomarkersBlood ProteinsCytokinesEnzymesHormones

Identifiers

PMID32681124
PMCPMC7368084

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.