Evidence map›Paper›PMID 32680496›Full record

SynthesisBMC endocrine disorders2020

Associations between alcohol intake and diabetic retinopathy risk: a systematic review and meta-analysis.

Chen Chen, Zhaojun Sun, Weigang Xu, Jun Tan, Dan Li, Yiting Wu, Ting Zheng, Derong Peng

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC endocrine disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Chen ChenShanghai Jing 'an District Jiangning Road Community Health Service Center, Shanghai, China.
Zhaojun SunShanghai Jing 'an District Pengpuxincun Community Health Service Center, No.15 Pingshun Road, Jing 'an District, Shanghai, 200435, China.
Weigang XuShanghai Jing 'an District Pengpuxincun Community Health Service Center, No.15 Pingshun Road, Jing 'an District, Shanghai, 200435, China.
Jun TanShanghai Jing 'an District Pengpuxincun Community Health Service Center, No.15 Pingshun Road, Jing 'an District, Shanghai, 200435, China.
Dan LiShanghai Jing 'an District Pengpuxincun Community Health Service Center, No.15 Pingshun Road, Jing 'an District, Shanghai, 200435, China.
Yiting WuShanghai Jing 'an District Pengpuxincun Community Health Service Center, No.15 Pingshun Road, Jing 'an District, Shanghai, 200435, China.
Ting ZhengShanghai Jing 'an District Pengpuxincun Community Health Service Center, No.15 Pingshun Road, Jing 'an District, Shanghai, 200435, China.
Derong PengShanghai Jing 'an District Pengpuxincun Community Health Service Center, No.15 Pingshun Road, Jing 'an District, Shanghai, 200435, China. cc13916627775@163.com.
Community Health Center · US

Funding

Experimental study on the management mode of berberine combined with family doctors to delay retinopathy in community type II diabetic patients Community 2018SQ05Intervention study of berberine combined with comprehensive treatment for type II diabetic retinopathy in north Shanghai community TYS2018M008
6 · The paper itself

Abstract

backgroundSome previous studies have reported inconsistent results on the association between alcohol intake and diabetic retinopathy (DR) risk. This study aimed to evaluate the potential effects of alcohol intake on subsequent DR risk using a meta-analytic approach.

methodsThree electronic databases (PubMed, EmBase, and the Cochrane library) were systematically searched for observational studies from their inception till November 2019. The pooled odds ratio (OR) with 95% confidence interval (CI) were applied for the summary effect estimate using a random-effects model.

resultsA total of 15 studies (5 cohort studies, 4 case-control studies, and 6 cross-sectional studies) with 37,290 participants and 12,711 DR cases were selected for the final meta-analysis. The pooled OR indicated no significant association between alcohol intake and DR risk (OR: 0.91; 95%CI: 0.78-1.06; P = 0.225), irrespective of the studies being pooled cohort (OR: 0.95; 95%CI: 0.66-1.36; P = 0.761), case-control (OR: 0.97; 95%CI: 0.77-1.23; P = 0.818), or cross-sectional (OR: 0.86; 95%CI: 0.69-1.08; P = 0.190) ones. However, this association might have been affected by the type of diabetes mellitus and the adjusted status.

conclusionThe results of this study showed that the potential impact of alcohol intake on DR risk may differ according to the type of diabetes mellitus and adjusted status. Further large-scale, prospective cohort studies should be conducted to verify the findings of this study and to evaluate DR risk in relation to the dose and type of alcohol intake.

Indexed as

Alcohol DrinkingCohort StudiesDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Diabetic RetinopathyHumansPrognosisRisk FactorsAlcoholDiabetic retinopathyMeta-analysis

Identifiers

PMID32680496
PMCPMC7368775
OpenAlexW3043410504

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.