Evidence map›Paper›PMID 32679840›Full record

ArticleBiomolecules2020

Vitamin D Prevents Pancreatic Cancer-Induced Apoptosis Signaling of Inflammatory Cells.

Stefania Moz, Nicole Contran, Monica Facco, Valentina Trimarco, Mario Plebani, Daniela Basso

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Stefania MozDepartment of Medicine-DIMED, Laboratory Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy.
Nicole ContranDepartment of Medicine-DIMED, Laboratory Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy.
Monica FaccoDepartment of Medicine-DIMED, Hematology and Clinical Immunology Unit, University of Padova, 35128 Padua, Italy.ORCID 0000-0003-0100-5789
Valentina TrimarcoDepartment of Medicine-DIMED, Hematology and Clinical Immunology Unit, University of Padova, 35128 Padua, Italy.
Mario PlebaniDepartment of Medicine-DIMED, Laboratory Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy.ORCID 0000-0002-0270-1711
Daniela BassoDepartment of Medicine-DIMED, Laboratory Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy.ORCID 0000-0001-8745-6171
University of Padua · IT

Funding

Associazione Wirsung Onlus (Padova, Italy) 92137710288
6 · The paper itself

Abstract

Combined approaches based on immunotherapy and drugs supporting immune effector cell function might increase treatment options for pancreatic ductal adenocarcinoma (PDAC), vitamin D being a suitable drug candidate. In this study, we evaluated whether treatment with the vitamin D analogue, calcipotriol, counterbalances PDAC induced and SMAD4-associated intracellular calcium [Ca

Indexed as

CalcitriolCalciumCarcinoma, Pancreatic DuctalCell ProliferationCulture Media, ConditionedCytokinesHumansLymphocytesNF-kappa BPancreatic NeoplasmsSignal TransductionSmad4 ProteinTumor Necrosis Factor-alphaVitamin DcalcipotrieneCalcitriolCalciumCulture Media, ConditionedCytokinesNF-kappa BSmad4 ProteinSMAD4 protein, humanTumor Necrosis Factor-alphaVitamin Dcytokinesimmune systemintracellular calciumintracellular signaling pathwaysPDACvitamin D

Identifiers

PMID32679840
PMCPMC7408286
OpenAlexW3042552804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.