ArticleDiseases (Basel, Switzerland)2020
Impact of Acute Kidney Injury on Outcomes of Hospitalizations for Heat Stroke in the United States.
Article in Diseases (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Heatstroke Over the Past Decade: Risk Factors, Long-Term Health Consequences, and Preventive Measures.Journal of general internal medicine · 2026Pooled it
- Heat-Related Illness and Heatstroke: A Narrative and Clinical Review for Emergency Clinicians.Cureus · 2026Review
- Oxidative Stress in Heat Stress Nephropathy: Crosstalk.Oxidative medicine and cellular longevity · 2026Review
- Development and validation of the predictive scoring system for 90-day mortality in critical ill patients with exertional heatstroke.Renal failure · 2025Article
- One day of environment-induced heat stress causes injury to the murine kidney.Experimental physiology · 2025Article
- Proteomics-based monitoring of heatstroke recovery identifies molecular signatures of organ stress.Communications medicine · 2025Article
- Machine Learning-Based Prediction of Heatwave-Related Hospitalizations: A Case Study in Matam, Senegal.International journal of environmental research and public health · 2025Article
- Heat stroke with sepsis: A case report and review of the literature.The Journal of international medical research · 2025Review
- Prognostic nomogram for heat stroke patients based on rapidly accessible clinical indicators.Frontiers in medicine · 2025Article
- Climate change and nephrology.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023Article
- Risk Factor Analysis and Nomogram for Predicting In-Hospital Mortality in ICU Patients with Heat Stroke: A National Multicenter Study.Journal of multidisciplinary healthcare · 2023Article
- ZBP1 and heatstroke.Frontiers in immunology · 2023Review
- The association between albumin corrected anion gap and ICU mortality in acute kidney injury patients requiring continuous renal replacement therapy.Internal and emergency medicine · 2022Article
- Heat acclimation ameliorated heat stress-induced acute kidney injury and prevented changes in kidney macrophages and fibrosis.American journal of physiology. Renal physiology · 2022Article
- Racial Disparities in Climate Change-Related Health Effects in the United States.Current environmental health reports · 2022Review
- A mouse model of exertional heatstroke-related acute kidney injury.Annals of translational medicine · 2022Article
- Metabolomic profiling identifies a novel mechanism for heat stroke‑related acute kidney injury.Molecular medicine reports · 2021Article
- Clinical Characteristics and Risk Factors Associated With Acute Kidney Injury Inpatient With Exertional Heatstroke: An Over 10-Year Intensive Care Survey.Frontiers in medicine · 2021Article
- Thromboelastometry for assessment of hemostasis and disease severity in 42 dogs with naturally-occurring heatstroke.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
11 authors at 9 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aims to evaluate the risk factors and the association of acute kidney injury with treatments, complications, outcomes, and resource utilization in patients hospitalized for heat stroke in the United States. Hospitalized patients from years 2003 to 2014 with a primary diagnosis of heat stroke were identified in the National Inpatient Sample dataset. End stage kidney disease patients were excluded. The occurrence of acute kidney injury during hospitalization was identified using the hospital diagnosis code. The associations between acute kidney injury and clinical characteristics, in-hospital treatments, outcomes, and resource utilization were assessed using multivariable analyses. A total of 3346 hospital admissions were included in the analysis. Acute kidney injury occurred in 1206 (36%) admissions, of which 49 (1.5%) required dialysis. The risk factors for acute kidney injury included age 20-39 years, African American race, obesity, chronic kidney disease, congestive heart failure, and rhabdomyolysis, whereas age <20 or ≥60 years were associated with lower risk of acute kidney injury. The need for mechanical ventilation and blood transfusion was higher when acute kidney injury occurred. Acute kidney injury was associated with electrolyte and acid-base derangements, sepsis, acute myocardial infarction, ventricular arrhythmia or cardiac arrest, respiratory, circulatory, liver, neurological, hematological failure, and in-hospital mortality. Length of hospital stay and hospitalization cost were higher in acute kidney injury patients. Approximately one third of heat stroke patients developed acute kidney injury during hospitalization. Acute kidney injury was associated with several complications, and higher mortality and resource utilization.
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Registered trials
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