Evidence map›Paper›PMID 32679815›Full record

ReviewInternational journal of molecular sciences2020

Nuclear Receptors, Ligands and the Mammalian B Cell.

Bart G Jones, Rhiannon R Penkert, Sherri L Surman, Robert E Sealy, Julia L Hurwitz

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Bart G JonesDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Rhiannon R PenkertDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Sherri L SurmanDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Robert E SealyDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Julia L HurwitzDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
St. Jude Children's Research Hospital · US

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
American Lebanese Syrian Associated Charities ALSACNational Institute of Allergy and Infectious Diseases Collaborative Influenza Vaccine Innovation Centers (CIVICs) contract 75N93019C00052NCI NIH HHS P30 CA21765
6 · The paper itself

Abstract

Questions concerning the influences of nuclear receptors and their ligands on mammalian B cells are vast in number. Here, we briefly review the effects of nuclear receptor ligands, including estrogen and vitamins, on immunoglobulin production and protection from infectious diseases. We describe nuclear receptor interactions with the B cell genome and the potential mechanisms of gene regulation. Attention to the nuclear receptor/ligand regulation of B cell function may help optimize B cell responses, improve pathogen clearance, and prevent damaging responses toward inert- and self-antigens.

Indexed as

AnimalsB-LymphocytesGene Expression RegulationHumansImmunityImmunoglobulinsReceptors, SteroidThyroid HormonesVitamin AVitamin DImmunoglobulinsReceptors, SteroidThyroid HormonesVitamin AVitamin Destrogenimmunoglobulinregulatory elementsvitamins

Identifiers

PMID32679815
PMCPMC7404052
OpenAlexW3043294448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.