Evidence map›Paper›PMID 32679799›Full record

ArticleInternational journal of molecular sciences2020

Biodistribution PET/CT Study of Hemoglobin-DFO-

Łukasz Kiraga, Gabriele Cerutti, Agata Braniewska, Damian Strzemecki, Zuzanna Sas, Alberto Boffi, Carmelinda Savino, Linda Celeste Montemiglio, Daniel Turnham, Gillian Seaton and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 3 countries.

Łukasz KiragaDepartment of Cancer Biology, Institute of Biology, Warsaw University of Life Sciences, 02-787 Warsaw, Poland.
Gabriele CeruttiDepartment of Biochemical Sciences "Alessandro Rossi Fanelli", Sapienza University of Rome, 00-185 Rome, Italy.ORCID 0000-0002-9081-7561
Agata BraniewskaDepartment of Immunology, Medical University of Warsaw, 02-097 Warsaw, Poland.
Damian StrzemeckiDepartment of Immunology, Medical University of Warsaw, 02-097 Warsaw, Poland.
Zuzanna SasDepartment of Immunology, Medical University of Warsaw, 02-097 Warsaw, Poland.
Alberto BoffiDepartment of Biochemical Sciences "Alessandro Rossi Fanelli", Sapienza University of Rome, 00-185 Rome, Italy.
Carmelinda SavinoInstitute of Molecular Biology and Pathology, National Research Council, 00-185 Rome, Italy.ORCID 0000-0002-1602-4838
Linda Celeste MontemiglioInstitute of Molecular Biology and Pathology, National Research Council, 00-185 Rome, Italy.
Daniel TurnhamEuropean Cancer Stem Cell Research Institute (ECSCRI), School of Biosciences, Haydn Ellis Building, Cardiff University, Cardiff CF24 4HQ, Wales, UK.
Gillian SeatonEuropean Cancer Stem Cell Research Institute (ECSCRI), School of Biosciences, Haydn Ellis Building, Cardiff University, Cardiff CF24 4HQ, Wales, UK.
Alessandra BonamoreDepartment of Biochemical Sciences "Alessandro Rossi Fanelli", Sapienza University of Rome, 00-185 Rome, Italy.
Richard ClarksonEuropean Cancer Stem Cell Research Institute (ECSCRI), School of Biosciences, Haydn Ellis Building, Cardiff University, Cardiff CF24 4HQ, Wales, UK.
Adam M DabkowskiWales Research & Diagnostic PET Imaging Centre (PETIC), School of Medicine, Heath Park, Cardiff University, Cardiff CF14 4XN, Wales, UK.
Stephen J PaiseyWales Research & Diagnostic PET Imaging Centre (PETIC), School of Medicine, Heath Park, Cardiff University, Cardiff CF14 4XN, Wales, UK.
Bartłomiej TaciakDepartment of Cancer Biology, Institute of Biology, Warsaw University of Life Sciences, 02-787 Warsaw, Poland.
Paulina KucharzewskaDepartment of Cancer Biology, Institute of Biology, Warsaw University of Life Sciences, 02-787 Warsaw, Poland.
Tomasz P RygielDepartment of Immunology, Medical University of Warsaw, 02-097 Warsaw, Poland.
Magdalena KrólDepartment of Cancer Biology, Institute of Biology, Warsaw University of Life Sciences, 02-787 Warsaw, Poland.
Cardiff University · GBMedical University of Warsaw · PLWarsaw University of Life Sciences · PLSapienza University of Rome · ITInstitute of Molecular Biology and Pathology · IT

Funding

EU H2020 Project "X-Probe n° 637295European Community's Seventh Framework Programme (FP7/2007-2013) n° 312284European Research Council Starting Grant McHAP: 715048Fundacja na rzecz Nauki Polskiej TEAM TECH/2016/1/8
6 · The paper itself

Abstract

Proteins, as a major component of organisms, are considered the preferred biomaterials for drug delivery vehicles. Hemoglobin (Hb) has been recently rediscovered as a potential drug carrier, but its use for biomedical applications still lacks extensive investigation. To further explore the possibility of utilizing Hb as a potential tumor targeting drug carrier, we examined and compared the biodistribution of Hb in healthy and lung tumor-bearing mice, using for the first time

Indexed as

Drug Delivery SystemsAnimalsCell Line, TumorCoordination ComplexesDeferoxamineDrug CarriersFemaleHemoglobinsHumansLungLung NeoplasmsMiceMice, Inbred BALB CModels, MolecularPositron Emission Tomography Computed TomographyRadioisotopesCoordination ComplexesDeferoxamineDrug CarriersHemoglobinsRadioisotopesZirconiumZirconium-8989Zrbiodistributionhemoglobinimmune cellsmaleimide-deferoxaminePET/CTprotein drug carriertumor

Identifiers

PMID32679799
PMCPMC7404105
OpenAlexW3042974489

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.