ArticleMaterials (Basel, Switzerland)2020
New Nanofibers Based on Protein By-Products with Bioactive Potential for Tissue Engineering.
Article in Materials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 24 citations in OpenAlex.
- Donkey Gelatin and Keratin Nanofibers Loaded with Antioxidant Agents for Wound Healing Dressings.Gels (Basel, Switzerland) · 2024Article
- The Influence of Gamma Radiation on Different Gelatin Nanofibers and Gelatins.Gels (Basel, Switzerland) · 2024Article
- Bioactivity and Thermal Stability of Collagen-Chitosan Containing Lemongrass Essential Oil for Potential Medical Applications.Polymers · 2022Article
- Bioactive Low Molecular Weight Keratin Hydrolysates for Improving Skin Wound Healing.Polymers · 2022Article
- Bioactive Collagen Hydrolysate-Chitosan/Essential Oil Electrospun Nanofibers Designed for Medical Wound Dressings.Pharmaceutics · 2021Article
- Collagen-Based Electrospun Materials for Tissue Engineering: A Systematic Review.Bioengineering (Basel, Switzerland) · 2021Review
- Sustainable Rabbit Skin Glue to Produce Bioactive Nanofibers for Nonactive Wound Dressings.Materials (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
12 authors at 6 institutions in 2 countries.
Funding
Abstract
Concentrated collagen hydrolysate (HC10CC), rabbit collagen glue (RCG), and keratin hydrolysate (KH) were investigated in terms of their extraction from mammalian by-products and processing by electrospinning. The electrospun nanofibers were characterized by scanning electron microscopy coupled with the energy dispersive X-ray spectroscopy (SEM/EDS), attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR), differential scanning calorimetry (DSC), and indentation tests. The cytotoxicity of the electrospun nanofibers was conducted on L929 fibroblast cells using MTT and LDH assays and cell morphology observations. The electrospun RCG and KH nanofibers morphology showed an average size of nanofibers ranging between 44 and 410 nm, while the electrospun HC10CC nanofibers exhibited higher sizes. The ATR-FTIR spectra performed both on extracted proteins and electrospun nanofibers showed that the triple helix structure of collagen is partially preserved. The results were in agreement with the circular dichroism analysis for protein extracts. Furthermore, the viscoelastic properties of electrospun KH nanofibers were superior to those of electrospun RCG nanofibers. Based on both in vitro quantitative and qualitative analysis, the electrospun nanofibers were not cytotoxic, inducing a healthy cellular response. The results of new electrospun protein-based nanofibers may be useful for further research on bioactive properties of these nanofibers for tissue engineering.
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Registered trials
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