ArticleMolecules (Basel, Switzerland)2020
Antianhedonic and Antidepressant Effects of Affron
Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Therapeutic Potential of Saffron Extract in Mild Depression: A Study of Its Role on Anhedonia in Rats and Humans.Phytotherapy research : PTR · 2025Trial
- From Stigma to Therapy: Pharmacological Insights into Saffron Bioactives for Major Non-Communicable Diseases.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Temporal gene expression profiling suggests stage-specific regulation of apocarotenoid biosynthesis genes during stigma development inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2025Article
- Novel Insights into Dietary Bioactive Compounds and Major Depressive Disorders: Evidence from Animal Studies and Future Perspectives.The Journal of nutrition · 2025Review
- The Potential of Selected Plants and Their Biologically Active Molecules in the Treatment of Depression and Anxiety Disorders.International journal of molecular sciences · 2025Review
- Antidepressive and anxiolytic effects of a combination of Saffron and Chamomile in rats and their relationship with serotonin using methods.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2025Article
- Exploring the Potential of Saffron as a Therapeutic Agent in Depression Treatment: A Comparative Review.The Yale journal of biology and medicine · 2024Review
- Effects of Saffron Extract (AffronNutrients · 2023Article
- Effects of Supplementation with the Standardized Extract of Saffron (affronAntioxidants (Basel, Switzerland) · 2023Article
- Current Knowledge of the Antidepressant Activity of Chemical Compounds fromPharmaceuticals (Basel, Switzerland) · 2022Review
- RNA-seq based transcriptome analysis of ethanol extract of saffron protective effect against corticosterone-induced PC12 cell injury.BMC complementary medicine and therapies · 2022Article
- Prevention of Stress-Induced Depressive-like Behavior by Saffron Extract Is Associated with Modulation of Kynurenine Pathway and Monoamine Neurotransmission.Pharmaceutics · 2021Article
- Article
- Saffron Extract-Induced Improvement of Depressive-Like Behavior in Mice Is Associated with Modulation of Monoaminergic Neurotransmission.Nutrients · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anxiety and depression have high prevalence in the general population, affecting millions of people worldwide, but there is still a need for effective and safe treatments. Nutritional supplements have recently received a lot of attention, particularly saffron. Thus, several pre-clinical studies support a beneficial role for bioactive compounds, such as saffron, in anxiety and depression. Here we used an animal model of depression based on social isolation to assess the effects of affron
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.