Evidence map›Paper›PMID 32679582›Full record

ReviewPediatric research2021

A literature review of 2019 novel coronavirus (SARS-CoV2) infection in neonates and children.

Matteo Di Nardo, Grace van Leeuwen, Alessandra Loreti, Maria Antonietta Barbieri, Yit Guner, Franco Locatelli, Vito Marco Ranieri

Open access · hybridAbstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. SARS-CoV-2 Infection and COVID-19 in Children.Clinics in chest medicine · 2023
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Clinical, laboratory and imaging characteristics, and outcomes of hospitalized children with suspected COVID-19 infection: A report from Isfahan-Iran.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022
    Article
  18. Review
  19. Review
  20. Incidence of childhood cancer in Canada during the COVID-19 pandemic.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Matteo Di NardoPediatric Intensive Care Unit, Bambino Gesù Children Hospital, Rome, Italy. matteo.dinardo@opbg.net.
Grace van LeeuwenCardiac Intensive Care Unit, Sidra Hospital, Doha, Qatar.
Alessandra LoretiLibrary, Bambino Gesù Children Hospital, Rome, Italy.
Maria Antonietta BarbieriEmergency Department, Bambino Gesù Children Hospital, Palidoro, Rome, Italy.
Yit GunerPediatric Surgery, Children's Hospital of Orange County, Orange, CA, USA.
Franco LocatelliDepartment of Pediatric Hematology and Oncology, Bambino Gesù Children Hospital, Sapienza, University of Rome, Rome, Italy.
Vito Marco RanieriDepartment of Medical and Surgical Science, Anesthesia and Intensive Care, Policlinico di Sant'Orsola, Alma Mater, University of Bologna, Bologna, Italy.
Bambino Gesù Children's Hospital · ITChildren's Hospital of Orange County · USPoliclinico S.Orsola-Malpighi · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

At the time of writing, there are already millions of documented infections worldwide by the novel coronavirus 2019 (2019-nCoV or severe acute respiratory syndrome coronavirus 2 (SARS-CoV2)), with hundreds of thousands of deaths. The great majority of fatal events have been recorded in adults older than 70 years; of them, a large proportion had comorbidities. Since data regarding the epidemiologic and clinical characteristics in neonates and children developing coronavirus disease 2019 (COVID-19) are scarce and originate mainly from one country (China), we reviewed all the current literature from 1 December 2019 to 7 May 2020 to provide useful information about SARS-CoV2 viral biology, epidemiology, diagnosis, clinical features, treatment, prevention, and hospital organization for clinicians dealing with this selected population. IMPACT: Children usually develop a mild form of COVID-19, rarely requiring high-intensity medical treatment in pediatric intensive care unit. Vertical transmission is unlikely, but not completely excluded. Children with confirmed or suspected COVID-19 must be isolated and healthcare workers should wear appropriate protective equipment. Some clinical features (higher incidence of fever, vomiting and diarrhea, and a longer incubation period) are more common in children than in adults, as well as some radiologic aspects (more patchy shadow opacities on CT scan images than ground-glass opacities). Supportive and symptomatic treatments (oxygen therapy and antibiotics for preventing/treating bacterial coinfections) are recommended in these patients.

Indexed as

SARS-CoV-2Age DistributionAntiviral AgentsChildCohort StudiesConservative TreatmentCoronaviridaeCOVID-19COVID-19 Drug TreatmentCOVID-19 TestingFacility Design and ConstructionHumansInfantInfant, NewbornLungOxygen Inhalation TherapyAntiviral Agents

Identifiers

PMID32679582
OpenAlexW3042230100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.