Evidence map›Paper›PMID 32679515›Full record

ArticleFoot (Edinburgh, Scotland)2020

Relationships within and between lower and upper extremity dysfunction in people with diabetes.

Mary K Hastings, Hyo-Jung Jeong, Christopher J Sorensen, Jennifer A Zellers, Ling Chen, Kathryn L Bohnert, Darrah Snozek, Michael J Mueller

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Foot (Edinburgh, Scotland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02616263 (Muscle, Joint and Movement Deterioration Contributing to Neuropathic Forefoot Deformity), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02616263 nacompletednot on this map

Muscle, Joint and Movement Deterioration Contributing to Neuropathic Forefoot Deformity

TypeinterventionalSponsorWashington University School of MedicineRan2016 to 2021Enrolled60ConditionsDiabetes Mellitus (DM)ArmsFoot exercise, Shoulder exercise
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Isokinetic assessment of muscle function according to physical activity level and cardiovascular risk in asymptomatic adults aged 20 to 80 years.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mary K HastingsProgram in Physical Therapy, Washington University School of Medicine, St. Louis, 63108, MO, United States. Electronic address: hastingsmk@wustl.edu.
Hyo-Jung JeongProgram in Physical Therapy, Washington University School of Medicine, St. Louis, 63108, MO, United States.
Christopher J SorensenBernard Becker Medical Library, Washington University School of Medicine, St. Louis, 63108, MO, United States.
Jennifer A ZellersProgram in Physical Therapy, Washington University School of Medicine, St. Louis, 63108, MO, United States.
Ling ChenDivision of Biostatistics, Washington University School of Medicine, St. Louis, 63110, MO, United States.
Kathryn L BohnertProgram in Physical Therapy, Washington University School of Medicine, St. Louis, 63108, MO, United States.
Darrah SnozekProgram in Physical Therapy, Washington University School of Medicine, St. Louis, 63108, MO, United States.
Michael J MuellerProgram in Physical Therapy, Washington University School of Medicine, St. Louis, 63108, MO, United States.
Washington University in St. Louis · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Brian N Finck · 1999 to 2026
$30.2M
MUSCLE, JOINT AND MOVEMENT DETERIORATION CONTRIBUTING TO NEUROPATHIC FOREFOOT DEFORMITYR01DK107809 · NIDDK · WASHINGTON UNIVERSITY · PI MARY K HASTINGS · 2016 to 2026
$4.3M
DOCTORAL TRAINING PROGRAM IN MOVEMENT SCIENCET32HD007434 · NICHD · WASHINGTON UNIVERSITY · PI Michael D Harris, Catherine Lang · 1993 to 2026
$4.2M
Diabetes-related Tendon Changes: Integrating Ex Vivo and In Vivo ApproachesF32DK123916 · NIDDK · WASHINGTON UNIVERSITY · PI ZELLERS, JENNIFER · 2019 to 2020
$127k
NCATS NIH HHS UL1 TR002345NICHD NIH HHS T32 HD007434NIDDK NIH HHS F32 DK123916NIDDK NIH HHS P30 DK056341NIDDK NIH HHS R01 DK107809
6 · The paper itself

Abstract

introductionDiabetes mellitus (DM) is associated with systemic musculoskeletal system impairments suggesting concurrent development of lower and upper extremity musculoskeletal problems. This study aims to examine relationships between lower and upper extremity function in people with DM.

methodsSixty people with type 2 DM and peripheral neuropathy [mean (standard deviation); 67(6) years old, DM duration 14(10) yrs] completed the following measures: 1) Self-reports of function: Foot and Ankle Ability Measure (FAAM; higher = better function) and Shoulder Pain and Disability Index (SPADI; lower = better function), 2) Range of motion (goniometry): ankle dorsiflexion and shoulder flexion, and 3) Strength: unilateral heel rise power (UHR, 3D kinetics) and hand grip dynamometry. Pearson correlations examined associations between lower and upper extremity measures, p < .05.

resultsForty of 60 (67%) reported pain/disability in both the foot/ankle and shoulder and 95% of study participants had some limitation in foot or shoulder function. Significant between extremity correlations: FAAM and SPADI (r = -0.39), ankle dorsiflexion and shoulder flexion range of motion (r = 0.35), and UHR and hand grip strength (r = 0.40). Significant within extremity correlations: FAAM and UHR (r = .47) and SPADI with shoulder flexion (r = -0.44).

conclusionUpper and lower extremity inter- and intra-relationships indicate systemic musculoskeletal impairments in people with DM. Healthcare practitioners should consider the potential for concurrent and disabling musculoskeletal problems in people with DM.

Indexed as

AgedBiomechanical PhenomenaDiabetes Mellitus, Type 2Disability EvaluationFemaleHand StrengthHumansLower ExtremityMalePain MeasurementRange of Motion, ArticularUpper ExtremityAnkleFootFoot and ankle ability measureGrip strengthShoulderShoulder pain and disability indexUnilateral heel rise

Identifiers

PMID32679515
PMCPMC7483835
OpenAlexW3014373368

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.