ArticleRespiratory physiology & neurobiology2020
High altitude reduces infection rate of COVID-19 but not case-fatality rate.
Article in Respiratory physiology & neurobiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04604249 (Prevalence of COVID-19 and Risk Factors Associated With Seroconversion in La Rinconada, the Highest City of the World - 5,100 m), which is not on this map. Cited by 54 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevalence of COVID-19 and Risk Factors Associated With Seroconversion in La Rinconada, the Highest City of the World - 5,100 m
Who cites it
54 citing papers in PubMed.
- Trial
- Altitude and case fatality rate from COVID-19 during the pandemic in Peru, 2020-2022.Revista peruana de medicina experimental y salud publica · 2026Article
- Chronic hypoxia adaptation at high altitude: a perspective on Its potential role in mortality in viral pneumonia-associated ARDS and implications for personalized critical care.Critical care (London, England) · 2026Review
- Evaluating the impact of altitudinal variations on COVID-19 mortality rates: a comprehensive analysis.BMC pulmonary medicine · 2025Article
- Death Risk Response of High-Altitude Resident Populations to COVID-19 Vaccine: A Retrospective Cohort Study.High altitude medicine & biology · 2025Article
- Article
- COVID-19 in the Tibet, China, the roof of the world: a comparative analysis of high-altitude residents and newcomers.BMC infectious diseases · 2024Article
- Differences in SARS-COV-2 seroprevalence in the population of Cusco, Peru.Global epidemiology · 2024Article
- Influence of Environmental Factors and Genome Diversity on Cumulative COVID-19 Cases in the Highland Region of China: Comparative Correlational Study.Interactive journal of medical research · 2024Article
- High altitudes, population density, and poverty: Unraveling the complexities of COVID-19 in Peru during the years 2020-2022.Preventive medicine reports · 2023Article
- Application of Machine Learning to Predict COVID-19 Spread via an Optimized BPSO Model.Biomimetics (Basel, Switzerland) · 2023Article
- A U-shaped protection of altitude against mortality and infection of COVID-19 in Peru: an ecological study.BMC public health · 2023Article
- Constructing a Learning Curve to Discuss the Medical Treatments and the Effect of Vaccination of COVID-19.Healthcare (Basel, Switzerland) · 2023Article
- Solar desalination/purification (solar stills, humidification-dehumidification, solar disinfection) in high altitude during COVID19: Insights of gastrointestinal manifestations and systems' mechanism.Journal of hazardous materials advances · 2023Article
- Article
- Factors Associated with COVID-19 Death in a High-Altitude Peruvian Setting during the First 14 Months of the Pandemic: A Retrospective Multicenter Cohort Study in Hospitalized Patients.Tropical medicine and infectious disease · 2023Article
- Environment and COVID-19 incidence: A critical review.Journal of environmental sciences (China) · 2023Review
- Efficacy of Nirmatrelvir-Ritonavir versus Azvudine for COVID-19 Treatment in Tibet: A Retrospective Study.Infection and drug resistance · 2023Article
- Article
- Potential long-term effects of SARS-CoV-2 infection on the pulmonary vasculature: Multilayered cross-talks in the setting of coinfections and comorbidities.PLoS pathogens · 2023Review
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3 authors.
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Abstract
Coronavirus disease 19 (COVID-19) is a pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). It is suggested that life at high altitude may reduce COVID-19 infections and case-fatality rates (cases/deaths). We study data from Peru COVID-19 pandemics, which first case was recorded on March 6th, 2020. By June 13, 2020 there were 6498 deaths, and 224,132 SARS-CoV-2 positives. Using data from 185 capitals of provinces with altitudes ranging from 3 to 4342 m, we confirm previous reports that infection with COVID-19 at high altitude is reduced. However, case-fatality rate is not dependent of altitude. We have also presented first evidence that female protection towards death by COVID-19 is reduced as altitude of residence increases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.