Evidence map›Paper›PMID 32678349›Full record

ArticleEye (London, England)2021

Iodine-125 interstitial brachytherapy for malignant lacrimal sac tumours: an innovative technique.

Ping Wang, Nan Ma, Shaobo Zhang, Xiaona Ning, Chenjun Guo, Qiong Zhang, Qilin Cheng, Yangjun Li

Open access · bronzeAbstract read
In one paragraph

Article in Eye (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ping Wang *Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Nan Ma *Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Shaobo ZhangDepartment of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Xiaona NingDepartment of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Chenjun GuoDepartment of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Qiong ZhangDepartment of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Qilin ChengDepartment of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Yangjun LiDepartment of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China. liyjun1969@126.com.ORCID http://orcid.org/0000-0001-7206-452X
Air Force Medical University · CNTang Du Hospital · CN

Funding

National Natural Science Foundation of China (National Science Foundation of China) 81800808Natural Science Foundation of Shaanxi Province (Shaanxi Province Natural Science Foundation) 2016JM8012
6 · The paper itself

Abstract

objectivesPrimary malignant tumours of the lacrimal sac are rare, surgery and radiotherapy may induce substantial side effects for patients. Here, this article reports an innovative technique of interstitial brachytherapy developed for the treatment of malignant lacrimal sac tumours. PATIENTS AND

methodsFour patients (male 3, female 1), with an average age of 52.7 years (range 41-72 years), were individually diagnosed with squamous cell carcinoma, adenocarcinoma, adenoid cystic carcinoma and lymphoma. All patients received Iodine-125 interstitial brachytherapy after surgical resection for malignant lacrimal sac tumours. Visual function examination (vision, intraocular tension, fundus photography, fluorescein angiography, and optical coherence tomography) and CT/MRI/PET-MRI were performed to look for signs of recurrent tumours or metastasis.

resultsFour patients were followed for an average of 28 months (range, 23-37 months). All patients were free from local disease. Their visual function was normal, and CT/MRI did not reveal any tumour recurrence.

conclusionsIodine-125 interstitial brachytherapy can be used as an alternative to wide excision or exenteration of these tumours. There was good local control, reasonable maintenance of vision, and good cosmesis.

Indexed as

BrachytherapyLacrimal Apparatus DiseasesNasolacrimal DuctAdultAgedFemaleHumansIodine RadioisotopesMaleMiddle AgedNeoplasm Recurrence, LocalRetrospective StudiesIodine-125Iodine Radioisotopes

Identifiers

PMID32678349
PMCPMC8115631
OpenAlexW3043413217

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.