ArticleCommunications biology2020
A PIP
Erratum issuedOpen access · goldAbstract read
In one paragraph
Article in Communications biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.
0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.7field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 35 citations in OpenAlex.
- Docking-based virtual screening: Past, present, and future.Biophysical journal · 2026Review
- The SIMDA framework maps PIP2-binding sites regulating the KCNQ1 channel.Nature communications · 2026Article
- Barium senses subtle pore changes in a voltage-gated KScience advances · 2026Article
- Cannabidiol inhibits both human KActa pharmacologica Sinica · 2026Article
- Secondary structure transitions and dual PIP2 binding define cardiac KCNQ1-KCNE1 channel gating.Cell research · 2025Article
- Targeting the ICirculation research · 2024Article
- Article
- Ancient medicinal plant rosemary contains a highly efficacious and isoform-selective KCNQ potassium channel opener.Communications biology · 2023Article
- Targeting ion channels with ultra-large library screening for hit discovery.Frontiers in molecular neuroscience · 2023Review
- An allosteric modulator activates BK channels by perturbing coupling between CaNature communications · 2022Article
- Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Electro-mechanical coupling of KCNQ channels is a target of epilepsy-associated mutations and retigabine.Science advances · 2022Article
- Two HCN4 Channels Play Functional Roles in the Zebrafish Heart.Frontiers in physiology · 2022Article
- PIPCommunications biology · 2021Article
- Mapping Electromechanical Coupling Pathways in Voltage-Gated Ion Channels: Challenges and the Way Forward.Journal of molecular biology · 2021Review
- From Bench to Biomolecular Simulation: Phospholipid Modulation of Potassium Channels.Journal of molecular biology · 2021Review
- Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Insights into Cardiac IKs (KCNQ1/KCNE1) Channels Regulation.International journal of molecular sciences · 2020Review
- Calmodulin acts as a state-dependent switch to control a cardiac potassium channel opening.Science advances · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
18 authors at 4 institutions in 1 country.
Yongfeng Liu *Department of Biomedical Engineering, Center for the Investigation of Membrane Excitability Disorders, Cardiac Bioelectricity and Arrhythmia Center, Washington University in Saint Louis, Saint Louis, MO, 63130, USA.ORCID http://orcid.org/0000-0002-8649-7892
Xianjin Xu *Dalton Cardiovascular Research Center, Department of Physics and Astronomy, Department of Biochemistry, Institute for Data Science & Informatics, University of Missouri, Columbia, MO, 65211, USA.
Junyuan Gao *Department of Physiology and Biophysics, and Institute for Molecular Cardiology, Stony Brook University, Stony Brook, NY, 11794, USA.
Moawiah M NaffaaDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Disorders, Cardiac Bioelectricity and Arrhythmia Center, Washington University in Saint Louis, Saint Louis, MO, 63130, USA.
Hongwu LiangDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Disorders, Cardiac Bioelectricity and Arrhythmia Center, Washington University in Saint Louis, Saint Louis, MO, 63130, USA.
Jingyi ShiDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Disorders, Cardiac Bioelectricity and Arrhythmia Center, Washington University in Saint Louis, Saint Louis, MO, 63130, USA.
Hong Zhan WangDepartment of Physiology and Biophysics, and Institute for Molecular Cardiology, Stony Brook University, Stony Brook, NY, 11794, USA.ORCID http://orcid.org/0000-0002-3371-2309
Nien-Du YangDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Disorders, Cardiac Bioelectricity and Arrhythmia Center, Washington University in Saint Louis, Saint Louis, MO, 63130, USA.ORCID http://orcid.org/0000-0002-5261-7382
Panpan HouDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Disorders, Cardiac Bioelectricity and Arrhythmia Center, Washington University in Saint Louis, Saint Louis, MO, 63130, USA.ORCID http://orcid.org/0000-0001-7694-2262
Wenshan ZhaoDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Disorders, Cardiac Bioelectricity and Arrhythmia Center, Washington University in Saint Louis, Saint Louis, MO, 63130, USA.
Kelli McFarland WhiteDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Disorders, Cardiac Bioelectricity and Arrhythmia Center, Washington University in Saint Louis, Saint Louis, MO, 63130, USA.
Wenjuan KongDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Disorders, Cardiac Bioelectricity and Arrhythmia Center, Washington University in Saint Louis, Saint Louis, MO, 63130, USA.
Alex DouDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Disorders, Cardiac Bioelectricity and Arrhythmia Center, Washington University in Saint Louis, Saint Louis, MO, 63130, USA.
Amy CuiDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Disorders, Cardiac Bioelectricity and Arrhythmia Center, Washington University in Saint Louis, Saint Louis, MO, 63130, USA.
Guohui ZhangDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Disorders, Cardiac Bioelectricity and Arrhythmia Center, Washington University in Saint Louis, Saint Louis, MO, 63130, USA.
Ira S CohenDepartment of Physiology and Biophysics, and Institute for Molecular Cardiology, Stony Brook University, Stony Brook, NY, 11794, USA. ira.cohen@stonybrook.edu.
Xiaoqin ZouDalton Cardiovascular Research Center, Department of Physics and Astronomy, Department of Biochemistry, Institute for Data Science & Informatics, University of Missouri, Columbia, MO, 65211, USA. ZouX@missouri.edu.
Jianmin CuiDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Disorders, Cardiac Bioelectricity and Arrhythmia Center, Washington University in Saint Louis, Saint Louis, MO, 63130, USA. jcui@wustl.edu.ORCID http://orcid.org/0000-0002-9198-6332
Washington University in St. Louis · USStony Brook University · USUniversity of Missouri · USStony Brook Medicine · US
Funding
MANIPULATING IKS AS A THERAPEUTIC APPROACH TO CARDIAC ARRHYTHMIASR01HL126774 · NHLBI · WASHINGTON UNIVERSITY · PI CUI, JIANMIN · 2015 to 2018
$3.1MStructure prediction and in silico screening of protein-peptide interactionsR35GM136409 · NIGMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI XIAOQIN ZOU · 2020 to 2026
$2.9MDatabase and software development for protein-nucleic acid structure predicationR01GM109980 · NIGMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI ZOU, XIAOQIN · 2015 to 2019
$1.5MAmerican Heart Association-American Stroke Association 18POST34030203NHLBI NIH HHS HL126774NHLBI NIH HHS R01 HL126774NIGMS NIH HHS R01 GM109980NIGMS NIH HHS R35 GM136409
Abstract
KCNQ family K
Indexed as
Action PotentialsAnimalsComputer SimulationGuinea PigsKCNQ1 Potassium ChannelKCNQ Potassium ChannelsMyocytes, CardiacOocytesPatch-Clamp TechniquesPhosphatidylinositol 4,5-DiphosphateProtein Structure, TertiaryXenopus laevisKCNQ1 Potassium ChannelKCNQ Potassium ChannelsPhosphatidylinositol 4,5-Diphosphate
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.