Evidence map›Paper›PMID 32678225›Full record

ArticleScientific reports2020

Imbalances in the disposition of estrogen and naphthalene in breast cancer patients: a potential biomarker of breast cancer risk.

Dar-Ren Chen, Wei-Chung Hsieh, Yi-Lun Liao, Kuo-Juei Lin, Yu-Fen Wang, Po-Hsiung Lin

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Quo vadis blood protein adductomics?Archives of toxicology · 2022
    Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Dar-Ren ChenComprehensive Breast Cancer Center, Changhua Christian Hospital, Changhua, 500, Taiwan.
Wei-Chung HsiehDepartment of Laboratory Medicine, Da-Chien General Hospital, Miaoli, 360, Taiwan.
Yi-Lun LiaoDepartment of Environmental Engineering, National Chung Hsing University, Taichung, 402, Taiwan.
Kuo-Juei LinDepartment of Surgery, E-Da Hospital, I-Shou University, Kaohsiung, 824, Taiwan.
Yu-Fen WangCancer Research Center, Department of Research, Changhua Christian Hospital, Changhua, 500, Taiwan.
Po-Hsiung LinDepartment of Environmental Engineering, National Chung Hsing University, Taichung, 402, Taiwan. pohsiunglin@yahoo.com.
Changhua Christian Hospital · TWNational Chung Hsing University · TWE-Da Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elevation of naphthoquinones and estrogen quinones, which are reactive metabolites of naphthalene and estrogen, is thought to be an important indicator of naphthalene- and estrogen-induced carcinogenesis. We compared background levels of naphthalene and estrogen quinone-derived adducts in serum albumin (Alb) from 143 women with breast cancer and 119 healthy controls. Cysteinyl adducts of naphthoquinones, including 1,2-naphthoquinone (1,2-NPQ) and 1,4-naphthoquinone (1,4-NPQ), and estrogen quinones, including estrogen-2,3-quinones (E

Indexed as

AdultAgedBiomarkers, TumorBreast NeoplasmsCase-Control StudiesDisease SusceptibilityEstrogensFemaleGas Chromatography-Mass SpectrometryHumansMiddle AgedNaphthalenesPrognosisRiskYoung AdultBiomarkers, TumorEstrogensNaphthalenes

Identifiers

PMID32678225
PMCPMC7366907
OpenAlexW3043597060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.