Evidence map›Paper›PMID 32678145›Full record

ArticleScientific reports2020

Global distribution of epidemic-related Shiga toxin 2 encoding phages among enteroaggregative Escherichia coli.

Keiko Kimata, Kenichi Lee, Masanori Watahiki, Junko Isobe, Makoto Ohnishi, Sunao Iyoda

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Atypical diarrhoeagenicEpidemiology and infection · 2023
    Article
  6. An outbreak of food poisoning due toEpidemiology and infection · 2021
    Article
  7. Article
  8. Migratory birds as a potential overseas transmitter of Shiga toxin-producingInternational journal of veterinary science and medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Keiko KimataDepartment of Bacteriology, Toyama Institute of Health, Toyama, 9390363, Japan.
Kenichi LeeDepartment of Bacteriology I, National Institute of Infectious Diseases, Tokyo, 1628640, Japan. leek@niid.go.jp.
Masanori WatahikiDepartment of Bacteriology, Toyama Institute of Health, Toyama, 9390363, Japan.
Junko IsobeDepartment of Bacteriology, Toyama Institute of Health, Toyama, 9390363, Japan.
Makoto OhnishiDepartment of Bacteriology I, National Institute of Infectious Diseases, Tokyo, 1628640, Japan.
Sunao IyodaDepartment of Bacteriology I, National Institute of Infectious Diseases, Tokyo, 1628640, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the Shiga toxin-producing enteroaggregative Escherichia coli (Stx-EAEC) O104:H4 strain caused a massive outbreak across Europe in 2011, the importance of Stx-EAEC has attracted attention from a public health perspective. Two Stx-EAEC O86 isolates were obtained from patients with severe symptoms in Japan in 1999 and 2015. To characterize the phylogeny and pathogenic potential of these Stx-EAEC O86 isolates, whole-genome sequence analyses were performed by short-and long-read sequencing. Among genetically diverse E. coli O86, the Stx-EAEC O86 isolates were clustered with the EAEC O86:H27 ST3570 subgroup. Strikingly, there were only two loci with single nucleotide polymorphisms (SNPs) between the Stx2a phage of a Japanese O86:H27 isolate and that of the European epidemic-related Stx-EAEC O104:H4 isolate. These results provide evidence of global distribution of epidemic-related Stx2a phages among various lineages of E. coli with few mutations.

Indexed as

Disease OutbreaksEnteropathogenic Escherichia coliEpidemicsEscherichia coli InfectionsGene OrderGenome, BacterialHumansJapanShiga-Toxigenic Escherichia coliShiga Toxin 2VirulenceWhole Genome SequencingShiga Toxin 2

Identifiers

PMID32678145
PMCPMC7366661

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.