Evidence map›Paper›PMID 32677953›Full record

ArticleHealth and quality of life outcomes2020

Health-related quality of life in women with polycystic ovary syndrome attending to a tertiary hospital in Southeastern Spain: a case-control study.

María L Sánchez-Ferrer, Evdochia Adoamnei, María T Prieto-Sánchez, Jaime Mendiola, Shiana Corbalán-Biyang, Miriam Moñino-García, Joaquín A Palomar-Rodríguez, Alberto M Torres-Cantero

Abstract read
In one paragraph

Article in Health and quality of life outcomes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  16. Reducing research wastage by starting off on the right foot: optimally framing the research question.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

María L Sánchez-FerrerDepartment of Obstetrics & Gynecology, "Virgen de la Arrixaca" University Clinical Hospital, 30120, El Palmar (Murcia), Spain.
Evdochia AdoamneiInstitute for Biomedical Research of Murcia, IMIB-Arrixaca, 30120, El Palmar (Murcia), Spain. evdochia.adoamnei@um.es.ORCID http://orcid.org/0000-0003-3633-2245
María T Prieto-SánchezDepartment of Obstetrics & Gynecology, "Virgen de la Arrixaca" University Clinical Hospital, 30120, El Palmar (Murcia), Spain.
Jaime MendiolaInstitute for Biomedical Research of Murcia, IMIB-Arrixaca, 30120, El Palmar (Murcia), Spain.
Shiana Corbalán-BiyangDepartment of Obstetrics & Gynecology, "Virgen de la Arrixaca" University Clinical Hospital, 30120, El Palmar (Murcia), Spain.
Miriam Moñino-GarcíaInstitute for Biomedical Research of Murcia, IMIB-Arrixaca, 30120, El Palmar (Murcia), Spain.
Joaquín A Palomar-RodríguezServicio de Planificación y Financiación Sanitaria, Consejería de Salud, Región de Murcia, 30001, Murcia, Spain.
Alberto M Torres-CanteroInstitute for Biomedical Research of Murcia, IMIB-Arrixaca, 30120, El Palmar (Murcia), Spain.

Funding

Fundación Séneca 19443/PI/14Instituto de Salud Carlos III PI13/01237
6 · The paper itself

Abstract

backgroundPolycystic ovary syndrome (PCOS) is a chronic condition with symptoms affecting many women at reproductive age and evaluating their health-related quality of Life (HRQoL) is an important issue. Moreover, differences in the HRQoL between women with different PCOS phenotypes have never been analyzed. Therefore, the aim of our study was to compare the HRQoL between women with PCOS -and its phenotypes- and controls attending to a tertiary hospital.

methodsA group of 117 women with PCOS and 153 controls were studied between 2014 and 2016. Controls were women without PCOS attending the gynecological outpatient clinic for routine examinations. Cases were women attending the same setting and diagnosed with PCOS. PCOS diagnose was performed following the Rotterdam Criteria and women were further classified by anovulatory or ovulatory phenotypic subtype. Women underwent physical and gynecological exams and completed health questionnaires including the Short Form-12v2. Eight scales and two component summary scores [Physical (PCS) and Mental (MCS), respectively] were calculated. Bivariate and multivariate analyses were performed to assess differences in HRQoL between women with PCOS and controls.

resultsAll women with PCOS and anovulatory PCOS presented lower score in PCS compared to controls [mean (95%CI): 53.7 (52.5-54.9) and 52.9 (51.5-54.4) vs. 55.8 (54.8-56.8); p-values< 0.01], as well as lower scores for five out of the eight scales (p-values < 0.05) after adjusting by age, body mass index, infertility, educational level and current occupation. No significant differences were observed for the MCS between women with or without PCOS or its phenotypic subtypes.

conclusionsHRQoL was significantly decreased in adult women with PCOS and its anovulatory phenotype compared to controls attending the outpatient clinic of a tertiary hospital. These results may have implications for the clinical practice and suggest the need for specific interventions in women with PCOS.

Indexed as

Quality of LifeAdultCase-Control StudiesFemaleHumansPolycystic Ovary SyndromeSpainSurveys and QuestionnairesTertiary Care CentersCase-control studyHealth-related quality of lifePolycystic ovary syndromeSF-12v2

Identifiers

PMID32677953
PMCPMC7364602

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.