ArticleBMC women's health2020
Serum 25 hydroxyvitamin D levels and affecting factors among preconception fertile women.
Article in BMC women's health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Effects of Age, Season, and Pregnancy History on Vitamin D Status in Women Seeking Preconception Care.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Article
- Diagnosis and Emerging Biomarkers of Cystic Fibrosis-Related Kidney Disease (CFKD).Journal of clinical medicine · 2025Review
- Review
- Physiology of Vitamin D-Focusing on Disease Prevention.Nutrients · 2024Review
- Association of serum vitamin D status with gestational diabetes mellitus and other laboratory parameters in early pregnant women.BMC pregnancy and childbirth · 2022Article
- What are the effects of vitamin D supplementation for term breastfed infants to prevent vitamin D deficiency and improve bone health? - A Cochrane Review summary with commentary.Journal of musculoskeletal & neuronal interactions · 2021Article
- Vitamin D status in women with dichorionic twin pregnancies and their neonates: a pilot study in China.BMC pregnancy and childbirth · 2021Observational
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Authors and funding
7 authors.
Funding
Abstract
backgroundRecent study found that vitamin D before conception was considered as a potential additional determinant for achieving pregnancy and live births. The study aimed to evaluate the serum 25 hydroxyvitamin D (25(OH)D) levels and its affecting factors among preconception fertile women.
methodsThis cross-sectional study enrolled 410 women aged 22-44 years who attended a preconception genetic counseling clinic from January 2018 to May 2019. Sociodemographic characteristics and reproductive history of women were collected, and height and weight were measured. Serum 25(OH)D concentration was assayed with chemiluminescence immunoassay. Descriptive statistics were used to examine serum 25(OH)D concentration, and socio-demographic characteristics and reproductive history among preconception women. Determinants of vitamin D deficiency and its affecting factors were assessed using χ2 test and logistic regression.
resultsFindings showed 84.4% of women had serum 25(OH)D concentration below 20 ng/mL. Women working indoors as well as without a history of childbirth had significantly lower 25(OH)D levels compared with those non-working individuals and having delivered a previous child (both P < 0.05). The 25(OH)D levels were the lowest in winter among that in spring, summer, and autumn (all P < 0.001). Women in winter have significantly elevated OR of 5.00 (95%CI 1.75-14.25) to develop vitamin D deficiency. Seasonal variation in serum 25(OH)D levels was not present in non-working individuals and women aged 31-44 years.
conclusionsVitamin D deficiency is common among preconception women especially nulliparous women and working women, which propose to screen serum 25(OH)D on preconception evaluation and emphasize need vitamin D supplements and get sunshine exposure.
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