Evidence map›Paper›PMID 32677585›Full record

ArticleJournal of child neurology2020

Pediatric Inflammatory and Autoimmune Neurologic Disorders at a Tertiary Medical Center.

Angela M Curcio, Jennifer M Bain, Erin S Beck, Wendy S Vargas

Open access · greenAbstract read
In one paragraph

Article in Journal of child neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Angela M CurcioDepartment of Neurology, Morgan Stanley Children's Hospital at 21611Columbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0001-7834-9569
Jennifer M BainDepartment of Neurology, Morgan Stanley Children's Hospital at 21611Columbia University Irving Medical Center, New York, NY, USA.
Erin S BeckDepartment of Translational Neuroradiology, 2511National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-7839-7958
Wendy S VargasDepartment of Neurology, Morgan Stanley Children's Hospital at 21611Columbia University Irving Medical Center, New York, NY, USA.
Morgan Stanley Children's Hospital · USNational Institutes of Health · US

Funding

The Educational Impact of Childhood-Onset Multiple SclerosisK23HD098312 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI VARGAS, WENDY · 2019 to 2021
$500k
NICHD NIH HHS K23 HD098312
6 · The paper itself

Abstract

objectivesTo describe the spectrum of pediatric inflammatory neurologic diseases and compare the sensitivity of ancillary testing for these diagnoses.

methodsWe analyzed clinical features and outcomes of 98 children with an immune-mediated central nervous system disorder. We compared sensitivities of each diagnostic modality.

resultsWe identified the following diagnoses: acute cerebellar ataxia (n = 14; 14.3%), acute demyelinating encephalomyelitis (n = 13; 13.3%), multiple sclerosis (MS) (n = 18; 18.4%), anti-

conclusionsWe found that MRI is useful for detecting multiple sclerosis and acute demyelinating encephalomyelitis, cerebrospinal fluid is helpful in diagnosing multiple sclerosis and anti-NMDAR encephalitis, and EEG is often abnormal in suspected anti-NMDAR encephalitis, acute demyelinating encephalomyelitis, and encephalitis not otherwise specified. Neurologic outcome at follow-up was unfavorable in patients with multiple sclerosis and anti-NMDAR encephalitis.

Indexed as

AdolescentAutoimmune Diseases of the Nervous SystemBrainChildChild, PreschoolElectroencephalographyFemaleHumansInfantMagnetic Resonance ImagingMaleRetrospective StudiesSensitivity and SpecificityTertiary Care Centersautoimmuneencephalitismultiple sclerosisneuroimmunologyoutcomepediatric

Identifiers

PMID32677585
PMCPMC7674214
OpenAlexW3043704334

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.