Evidence map›Paper›PMID 32677523›Full record

ArticleGlobal spine journal2021

Long-Term Residual-Mobility and Adjacent Segment Disease After Total Lumbar Disc Replacement.

Joep Kitzen, Timon F G Vercoulen, Martijn G M Schotanus, Sander M J van Kuijk, Nanne P Kort, Lodewijk W van Rhijn, Paul C P H Willems

Open access · goldAbstract read
In one paragraph

Article in Global spine journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Joep Kitzen199236Maastricht University Medical Centre, Maastricht, Netherlands.ORCID https://orcid.org/0000-0003-0417-8052
Timon F G Vercoulen199236Maastricht University Medical Centre, Maastricht, Netherlands.
Martijn G M SchotanusyZuyderland Medical Centre, Sittard-Geleen, Netherlands.
Sander M J van Kuijk199236Maastricht University Medical Centre, Maastricht, Netherlands.
Nanne P KortyZuyderland Medical Centre, Sittard-Geleen, Netherlands.
Lodewijk W van Rhijn199236Maastricht University Medical Centre, Maastricht, Netherlands.
Paul C P H Willems199236Maastricht University Medical Centre, Maastricht, Netherlands.
Maastricht University Medical Centre · NLZuyderland Medisch Centrum · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective cohort study.

objectivesTotal disc replacement (TDR) has been introduced in order to preserve segmental motion and thus reduce adjacent segment disease (ASD) as seen after spinal fusion. However, it is uncertain whether these presumed beneficial effects remain. The aim of this study was to evaluate the long-term incidence of ASD and residual-mobility in relation to clinical outcome.

methodsA total of 210 patients treated with lumbar TDR for degenerative disc disease were invited for follow-up. ASD was reported in case of severe degeneration in an adjacent disc at latest follow-up, or if an increase in disc degeneration was observed in these adjacent segments as compared to direct postoperative radiographs. Residual-mobility of the TDR was defined as a minimal rotation of 4.6° on flexion-extension radiographs. Patient-reported outcome measures were obtained.

resultsFifty-seven patients (27.1%) were lost to follow-up. In 32 patients (15.3%) a revision by spinal fusion had been performed. In 20 patients this revision had occurred ≥5 years after TDR and were included. Consequently, 141 patients were available for analysis (mean follow-up of 16.7 years). Residual-mobility was noted in 38.0%. No significant associations were observed between residual-mobility and the occurrence of ASD, or with clinical outcome. In addition, ASD and clinical outcome were not related either.

conclusionsIt appears that long-term preservation of motion after TDR is met for only a third of patients. However, residual-mobility is not associated with the occurrence of ASD, and both residual-mobility and ASD do not appear to be related to long-term clinical outcome.

Indexed as

degenerativedegenerative disc diseasedisc replacementlow back painlumbar

Identifiers

PMID32677523
PMCPMC8351064
OpenAlexW3039910581

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.