Observational studyPalliative medicine2020
The Palliative Performance Scale predicts mortality in hospitalized patients with COVID-19.
Observational study in Palliative medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Association of frailty with outcomes in individuals with COVID-19: A living review and meta-analysis.Journal of the American Geriatrics Society · 2021Pooled it
- What is the relationship between validated frailty scores and mortality for adults with COVID-19 in acute hospital care? A systematic review.Age and ageing · 2021Pooled it
- Frailty as a predictor of mortality among patients with COVID-19: a systematic review and meta-analysis.BMC geriatrics · 2021Pooled it
- The Impact of Frailty on COVID-19 Outcomes: A Systematic Review and Meta-analysis of 16 Cohort Studies.The journal of nutrition, health & aging · 2021Pooled it
- Observational
- Determining timeframes to death for imminently dying patients: a retrospective cohort study.BMC palliative care · 2025Article
- Perspectives and lived experiences of survivors and caregivers of COVID-19 patients in a teaching hospital in a tribal district of Chhattisgarh, India.Journal of family medicine and primary care · 2024Article
- Hospital-Based Palliative and End-of-Life Care in the COVID-19 Pandemic: A Scoping Review.The American journal of hospice & palliative care · 2022Article
- COVID-19 Management in a UK NHS Foundation Trust with a High Consequence Infectious Diseases Centre: A Retrospective Analysis.Medical sciences (Basel, Switzerland) · 2021Article
- Going Beyond the Do-Not-Resuscitate Order: Comparing the Care Received by Cancer Patients with Respect to Hospice Care Needs.Indian journal of palliative careArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCoronavirus disease 2019 (COVID-19) has a substantial mortality risk with increased rates in the elderly. We hypothesized that age is not sufficient, and that frailty measured by preadmission Palliative Performance Scale would be a predictor of outcomes. Improved ability to identify high-risk patients will improve clinicians' ability to provide appropriate palliative care, including engaging in shared decision-making about life-sustaining therapies.
aimTo evaluate whether preadmission Palliative Performance Scale predicts mortality in hospitalized patients with COVID-19.
designRetrospective observational cohort study of patients admitted with COVID-19. Palliative Performance Scale was calculated from the chart. Using logistic regression, Palliative Performance Scale was assessed as a predictor of mortality controlling for demographics, comorbidities, palliative care measures and socioeconomic status. SETTING/
participantsPatients older than 18 years of age admitted with COVID-19 to a single urban public hospital in New Jersey, USA.
resultsOf 443 admitted patients, we determined the Palliative Performance Scale score for 374. Overall mortality was 31% and 81% in intubated patients. In all, 36% (134) of patients had a low Palliative Performance Scale score. Compared with patients with a high score, patients with a low score were more likely to die, have do not intubate orders and be discharged to a facility. Palliative Performance Scale independently predicts mortality (odds ratio 2.89; 95% confidence interval 1.42-5.85).
conclusionsPreadmission Palliative Performance Scale independently predicts mortality in patients hospitalized with COVID-19. Improved predictors of mortality can help clinicians caring for patients with COVID-19 to discuss prognosis and provide appropriate palliative care including decisions about life-sustaining therapy.
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