Evidence map›Paper›PMID 32677385›Full record

ArticleKorean journal of radiology2020

Development and Validation of a Prognostic Nomogram Based on Clinical and CT Features for Adverse Outcome Prediction in Patients with COVID-19.

Yingyan Zheng, Anling Xiao, Xiangrong Yu, Yajing Zhao, Yiping Lu, Xuanxuan Li, Nan Mei, Dejun She, Dongdong Wang, Daoying Geng and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Korean journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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  15. What's New in theKorean journal of radiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yingyan Zheng *Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China.ORCID 0000-0002-6841-4563
Anling Xiao *Department of Radiology, FuYang No.2 People's Hospital, Fuyang, China.ORCID 0000-0003-2814-0470
Xiangrong YuDepartment of Radiology, Zhuhai People's Hospital, Zhuhai Hospital affiliated with Jinan University, Zhuhai, China.ORCID 0000-0003-2656-9847
Yajing ZhaoDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai, China.ORCID 0000-0002-9092-3241
Yiping LuDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai, China.ORCID 0000-0003-3241-9773
Xuanxuan LiDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai, China.ORCID 0000-0002-2171-2969
Nan MeiDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai, China.ORCID 0000-0001-8261-576X
Dejun SheDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai, China.ORCID 0000-0002-0143-659X
Dongdong WangDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai, China.ORCID 0000-0003-2737-6748
Daoying GengDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai, China.ORCID 0000-0001-9451-9687
Bo YinDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai, China. yinbo@fudan.edu.cn.ORCID 0000-0003-4134-8583
Fudan University · CNFuyang Maternity and Child Health Care Hospital · CNZhuhai People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of our study was to investigate the predictive abilities of clinical and computed tomography (CT) features for outcome prediction in patients with coronavirus disease (COVID-19). MATERIALS AND

methodsThe clinical and CT data of 238 patients with laboratory-confirmed COVID-19 in our two hospitals were retrospectively analyzed. One hundred sixty-six patients (103 males; age 43.8 ± 12.3 years) were allocated in the training cohort and 72 patients (38 males; age 45.1 ± 15.8 years) from another independent hospital were assigned in the validation cohort. The primary composite endpoint was admission to an intensive care unit, use of mechanical ventilation, or death. Univariate and multivariate Cox proportional hazard analyses were performed to identify independent predictors. A nomogram was constructed based on the combination of clinical and CT features, and its prognostic performance was externally tested in the validation group. The predictive value of the combined model was compared with models built on the clinical and radiological attributes alone.

resultsOverall, 35 infected patients (21.1%) in the training cohort and 10 patients (13.9%) in the validation cohort experienced adverse outcomes. Underlying comorbidity (hazard ratio [HR], 3.35; 95% confidence interval [CI], 1.67-6.71;

conclusionUnderlying comorbidity, lymphocyte count and crazy-paving sign were independent predictors of adverse outcomes. The prognostic nomogram based on the combination of clinical and CT features could be a useful tool for predicting adverse outcomes of patients with COVID-19.

Indexed as

BetacoronavirusAdultCoronavirus InfectionsCOVID-19FemaleHumansMaleMiddle AgedNomogramsPandemicsPneumonia, ViralPrognosisProportional Hazards ModelsRetrospective StudiesSARS-CoV-2Tomography, X-Ray ComputedCoronavirusCOVID-19CTNomogramPrognosis

Identifiers

PMID32677385
PMCPMC7369204
OpenAlexW3037974458

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.