ArticlePlant biotechnology journal2021
A large-scale genomic association analysis identifies the candidate causal genes conferring stripe rust resistance under multiple field environments.
Article in Plant biotechnology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 4 of them syntheses that pooled it.
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Who cites it
47 citing papers in PubMed, 4 syntheses or guidelines pooled it, 91 citations in OpenAlex.
- Meta-analysis of the quantitative trait loci associated with agronomic traits, fertility restoration, disease resistance, and seed quality traits in pigeonpea (Cajanus cajan L.).The plant genome · 2023Pooled it
- Pooled it
- Genome-wide meta-analysis of QTL for morphological related traits of flag leaf in bread wheat.PloS one · 2022Pooled it
- Meta-QTLs and candidate genes for stripe rust resistance in wheat.Scientific reports · 2021Pooled it
- Genetic dissection of a key dynamic growth period QTL for source-sink-related traits and its breeding application potential in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Wheat's war against stripe rust: Integrating host immunity, genomics and breeding for durable resistance.The plant genome · 2026Review
- Synthetic-augmented multimodal deep learning fuses dual-angle RGB images and phenology to unlock genotype-informative canopy structural trait in wheat.Plant phenomics (Washington, D.C.) · 2026Article
- LOX-A4 shapes Triticum urartu gene pools and contributions to the A subgenome of polyploid wheat.Nature communications · 2026Article
- The development and validation of a genotyping-by-target sequencing chip for fungal population genetic analysis.Stress biology · 2026Article
- Genome-wide association studies and candidate gene identification under salinity stress in bread wheat (Frontiers in plant science · 2026Article
- Genome-wide association mapping and candidate genes analysis of high-throughput image descriptors for wheat frost tolerance.Stress biology · 2025Article
- Genome-Wide Linkage Mapping of QTL for Adult-Plant Resistance to Stripe Rust in a Chinese Wheat Population Lantian 25 × Huixianhong.Plants (Basel, Switzerland) · 2025Article
- Genomics-driven discovery of superior alleles and genes for yellow rust resistance in wheat.Nature genetics · 2025Article
- Genetic loci and novel candidate causal genes for preharvest sprouting resistance in wheat (Triticum aestivum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Wheat TaNADPO Promotes Spot Blotch Resistance.Molecular plant pathology · 2025Article
- Markers Associated with Starch, Protein and Asparagine Content in Grain of Common Wheat.Genes · 2025Article
- Genome-Wide Association Study to Identify Soybean Lodging Resistance Loci and Candidate Genes.International journal of molecular sciences · 2025Article
- A system genetics analysis uncovers the regulatory variants controlling drought response in wheat.Plant biotechnology journal · 2025Article
- A large-scale multi-environment study dissecting adult-plant resistance haplotypes for stripe rust resistance in Australian wheat breeding populations.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Development and application of the GenoBaits WheatSNP16K array to accelerate wheat genetic research and breeding.Plant communications · 2025Article
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Authors and funding
16 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The incorporation of resistance genes into wheat commercial varieties is the ideal strategy to combat stripe or yellow rust (YR). In a search for novel resistance genes, we performed a large-scale genomic association analysis with high-density 660K single nucleotide polymorphism (SNP) arrays to determine the genetic components of YR resistance in 411 spring wheat lines. Following quality control, 371 972 SNPs were screened, covering over 50% of the high-confidence annotated gene space. Nineteen stable genomic regions harbouring 292 significant SNPs were associated with adult-plant YR resistance across nine environments. Of these, 14 SNPs were localized in the proximity of known loci widely used in breeding. Obvious candidate SNP variants were identified in certain confidence intervals, such as the cloned gene Yr18 and the major locus on chromosome 2BL, despite a large extent of linkage disequilibrium. The number of causal SNP variants was refined using an independent validation panel and consideration of the estimated functional importance of each nucleotide polymorphism. Interestingly, four natural polymorphisms causing amino acid changes in the gene TraesCS2B01G513100 that encodes a serine/threonine protein kinase (STPK) were significantly involved in YR responses. Gene expression and mutation analysis confirmed that STPK played an important role in YR resistance. PCR markers were developed to identify the favourable TraesCS2B01G513100 haplotype for marker-assisted breeding. These results demonstrate that high-resolution SNP-based GWAS enables the rapid identification of putative resistance genes and can be used to improve the efficiency of marker-assisted selection in wheat disease resistance breeding.
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