Evidence map›Paper›PMID 32677047›Full record

ArticleJournal of clinical laboratory analysis2020

A novel DSN-based fluorescence assay for MicroRNA-133a detection and its application for LVH diagnosis in maintenance hemodialysis patients.

Pei Huang, Xuedan Guo, Yan Jin, Qing Huang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical laboratory analysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Pei HuangDepartment of Oncology, Wuxi No. 2 People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Xuedan GuoDepartment of Oncology, Wuxi No. 2 People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.ORCID https://orcid.org/0000-0001-5117-3057
Yan JinDepartment of Gastroenterology, Wuxi No. 2 People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Qing HuangDepartment of Emergency, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Wuxi No.2 People's Hospital · CNWuxi People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Left ventricular hypertrophy (LVH) is the most powerful predictor of cardiovascular mortality in maintenance hemodialysis (MHD) patients. Circulating microRNA-133a (miR-133a) was reported to be a potential biomarker for LVH in MHD patients. The aim of this experiment is to establish a novel DSN (duplex-specific-nuclease)-based fluorescence assay for the ultrasensitive detection of miR-133a and investigate its application for LVH diagnosis in MHD patients. The results indicate DSN enzyme combined with ultrathin metallic MoS

Indexed as

Renal DialysisBiological AssayEndonucleasesFemaleFluorescenceHumansHypertrophy, Left VentricularMaleMicroRNAsMiddle AgedSensitivity and SpecificityEndonucleasesMicroRNAsMIRN133 microRNA, humanDSN-based fluorescence assayleft ventricular hypertrophymaintenance hemodialysisMicroRNA-133a

Identifiers

PMID32677047
PMCPMC7595923
OpenAlexW3042656726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.