ArticleParasitology research2020
First report of Cytauxzoon sp. infection in Germany: organism description and molecular confirmation in a domestic cat.
Article in Parasitology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 22 citations in OpenAlex.
- Molecular characterization of Cytauxzoon brasiliensis in domestic cats (Felis catus) from Rio de Janeiro state, Brazil: hematological findings.Veterinary research communications · 2026Article
- First Detection ofMicroorganisms · 2025Article
- Diversity ofPathogens (Basel, Switzerland) · 2025Article
- Feline immunodeficiency virus: current insights into pathogenesis, clinical impact, and advances in treatment and vaccine development.Frontiers in veterinary science · 2025Review
- Sylvatic vector-borne pathogens including Cytauxzoon europaeus in the European wildcat (Felis silvestris) from southwestern Germany.Parasites & vectors · 2024Article
- Vector-Borne Pathogens in Stray Cats in Eastern Germany (Thuringia).Animals : an open access journal from MDPI · 2023Article
- Screening of Domestic Cats from North-Eastern Hungary forPathogens (Basel, Switzerland) · 2023Article
- Article
- Apicomplexan haemoparasites in domestic cats in Romania.Parasites & vectors · 2023Article
- Molecular survey ofFrontiers in veterinary science · 2023Article
- The Piroplasmida Babesia, Cytauxzoon, and Theileria in farm and companion animals: species compilation, molecular phylogeny, and evolutionary insights.Parasitology research · 2022Review
- Article
- Cytauxzoon europaeus infections in domestic cats in Switzerland and in European wildcats in France: a tale that started more than two decades ago.Parasites & vectors · 2022Article
- Clinicopathological findings and risk factors associated withFrontiers in veterinary science · 2022Article
- Canine and Feline Parasitology: Analogies, Differences, and Relevance for Human Health.Clinical microbiology reviews · 2021Review
- Article
- Role of Zoo-Housed Animals in the Ecology of Ticks and Tick-Borne Pathogens-A Review.Pathogens (Basel, Switzerland) · 2021Review
- Arthropod-Borne Pathogens in Stray Cats from Northern Italy: A Serological and Molecular Survey.Animals : an open access journal from MDPI · 2020Article
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Cytauxzoonosis is described as an emerging tick-borne disease of domestic and wild felids caused by protozoans of the genus Cytauxzoon. While in the Americas the condition is described as a fatal disease, in Europe, reports on the clinical expression of the infection are scarce. This study describes the first case of Cytauxzoon sp. infection in Germany, in a domestic cat. A 6-year-old male domestic cat living in Saarlouis (Saarland) was presented with anorexia, lethargy and weight loss. The cat had an outdoor lifestyle and had not travelled abroad. Serum clinical chemistry analysis revealed azotaemia with markedly increased symmetric dimethylarginine, hypercreatinemia, hyperphosphatemia and hypoalbuminemia. Moreover, a mild non-regenerative anaemia was present. Approximately 1 year prior to these findings, the domestic cat was diagnosed with a feline immunodeficiency virus (FIV) infection. These results pointed toward a decreased glomerular filtration rate, presumably as a result of kidney dysfunction. Round to oval signet ring-shaped intraerythrocytic organisms, morphologically suggestive for a piroplasm, were revealed during blood smear evaluation with a degree of parasitaemia of 33.0%. PCR analyses and sequencing of a region of the 18S rRNA gene confirmed the presence of a Cytauxzoon sp. infection, with 99-100% nucleotide sequence identity with previously published Cytauxzoon sp. isolates. As this is the first molecularly confirmed Cytauxzoon sp. infection in a domestic cat in Germany, these findings suggest that cytauxzoonosis should be considered as a differential diagnosis in cases of anaemia in outdoor domestic cats, particularly in areas where wild felid populations are present.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.