Evidence map›Paper›PMID 32676898›Full record

ReviewRheumatology international2021

Behcet's disease with peripheral nervous system involvement successfully treated with golimumab: a case report and review of the literature.

Menghui Yao, Congcong Gao, Chunyi Zhang, Xueqi Di, Wenfang Liang, Wenbo Sun, Qianqian Wang, Zhaohui Zheng

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Rheumatology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Menghui YaoDepartment of Rheumatology, The First Affiliated Hospital of Zhengzhou University, 1 Eastern Jianshe Road, Zhengzhou, 450052, Henan, China.ORCID http://orcid.org/0000-0003-3062-7974
Congcong GaoDepartment of Rheumatology, The First Affiliated Hospital of Zhengzhou University, 1 Eastern Jianshe Road, Zhengzhou, 450052, Henan, China.ORCID http://orcid.org/0000-0003-1771-8847
Chunyi ZhangDepartment of Rheumatology, The First Affiliated Hospital of Zhengzhou University, 1 Eastern Jianshe Road, Zhengzhou, 450052, Henan, China.ORCID http://orcid.org/0000-0003-4544-7642
Xueqi DiDepartment of Rheumatology, The First Affiliated Hospital of Zhengzhou University, 1 Eastern Jianshe Road, Zhengzhou, 450052, Henan, China.ORCID http://orcid.org/0000-0001-9532-606X
Wenfang LiangDepartment of Rheumatology, The First Affiliated Hospital of Zhengzhou University, 1 Eastern Jianshe Road, Zhengzhou, 450052, Henan, China.ORCID http://orcid.org/0000-0001-6451-8915
Wenbo SunDepartment of Rheumatology, The First Affiliated Hospital of Zhengzhou University, 1 Eastern Jianshe Road, Zhengzhou, 450052, Henan, China.ORCID http://orcid.org/0000-0002-0454-1774
Qianqian WangDepartment of Rheumatology, The First Affiliated Hospital of Zhengzhou University, 1 Eastern Jianshe Road, Zhengzhou, 450052, Henan, China.ORCID http://orcid.org/0000-0002-8316-6254
Zhaohui ZhengDepartment of Rheumatology, The First Affiliated Hospital of Zhengzhou University, 1 Eastern Jianshe Road, Zhengzhou, 450052, Henan, China. fcczhengzh@zzu.edu.cn.ORCID http://orcid.org/0000-0003-3817-0171
First Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nervous system involvement is a rare and serious complication of Behcet's disease (BD), and the peripheral type is rarer. This article aimed to describe a case of BD with the peripheral nervous system (PNS) involvement and present a comprehensive literature review. One case of BD with PNS involvement was reported and related literature was retrospectively reviewed via PubMed/MEDLINE and Scopus database. The patient was resistant to traditional treatments, such as glucocorticoids and immunosuppressants, but had rapid quiescence after using golimumab. Our literature review suggests that the involved peripheral nerves in BD were diverse, the most common were the tibial nerves and peroneal nerves, vasculitis might be the main cause, and prednisone was still the cornerstone of treatment. TNF-α inhibitors have been increasingly used for refractory BD in recent years. This well-illustrated case demonstrates the potential benefit of golimumab to the patient with PNS involvement. Given the diversity and complexity of PNS involvement, we recommend golimumab as a new trial treatment in clinical practice.

Indexed as

AdultAntibodies, MonoclonalBehcet SyndromeFemaleHumansMaleMiddle AgedPeripheral Nervous System DiseasesTumor Necrosis Factor InhibitorsAntibodies, MonoclonalgolimumabTumor Necrosis Factor InhibitorsBehcet’s diseaseGolimumabPeripheral nervous system involvementPrednisone

Identifiers

PMID32676898
OpenAlexW3043428247

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.