Evidence map›Paper›PMID 32676606›Full record

ArticlebioRxiv : the preprint server for biology2020

SARS-CoV-2 infection induces germinal center responses with robust stimulation of CD4 T follicular helper cells in rhesus macaques.

Sonny R Elizaldi, Yashavanth Shaan Lakshmanappa, Jamin W Roh, Brian A Schmidt, Timothy D Carroll, Kourtney D Weaver, Justin C Smith, Jesse D Deere, Joseph Dutra, Mars Stone and 21 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

31 authors at 4 institutions in 1 country.

Sonny R ElizaldiCenter for Immunology and Infectious Diseases, UC Davis, CA.
Yashavanth Shaan LakshmanappaCenter for Immunology and Infectious Diseases, UC Davis, CA.
Jamin W RohCenter for Immunology and Infectious Diseases, UC Davis, CA.
Brian A SchmidtCenter for Immunology and Infectious Diseases, UC Davis, CA.
Timothy D CarrollCalifornia National Primate Research Center, UC Davis, CA.
Kourtney D WeaverDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA.
Justin C SmithDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA.
Jesse D DeereCalifornia National Primate Research Center, UC Davis, CA.
Joseph DutraCalifornia National Primate Research Center, UC Davis, CA.
Mars StoneDepartment of Laboratory Medicine, University of California, San Francisco, San Francisco, CA.
Rebecca Lee SammakCalifornia National Primate Research Center, UC Davis, CA.
Katherine J OlstadCalifornia National Primate Research Center, UC Davis, CA.
J Rachel ReaderCalifornia National Primate Research Center, UC Davis, CA.
Zhong-Min MaCalifornia National Primate Research Center, UC Davis, CA.
Nancy K NguyenCenter for Immunology and Infectious Diseases, UC Davis, CA.
Jennifer WatanabeCalifornia National Primate Research Center, UC Davis, CA.
Jodie UsachaenkoCalifornia National Primate Research Center, UC Davis, CA.
Ramya ImmareddyCalifornia National Primate Research Center, UC Davis, CA.
JoAnn L YeeCalifornia National Primate Research Center, UC Davis, CA.
Daniela WeiskopfCenter for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA.
Alessandro SetteCenter for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA.
Dennis Hartigan-O'ConnorCalifornia National Primate Research Center, UC Davis, CA.
Stephen J McSorleyCenter for Immunology and Infectious Diseases, UC Davis, CA.
John H MorrisonCalifornia National Primate Research Center, UC Davis, CA.
Nam K TranPathology and Laboratory Medicine, School of Medicine, UC Davis, CA.
Graham SimmonsDepartment of Laboratory Medicine, University of California, San Francisco, San Francisco, CA.
Michael P BuschDepartment of Laboratory Medicine, University of California, San Francisco, San Francisco, CA.
Pamela A KozlowskiDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA.
Koen K A Van RompayCalifornia National Primate Research Center, UC Davis, CA.
Christopher J MillerCenter for Immunology and Infectious Diseases, UC Davis, CA.
Smita S IyerCenter for Immunology and Infectious Diseases, UC Davis, CA.
University of California, Davis · USLouisiana State University Health Sciences Center New Orleans · USUniversity of California, San Francisco · USLa Jolla Institute for Immunology · US

Funding

Nonhuman Primate Reagent ResourceU24AI126683 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Diogo Magnani · 2016 to 2026
$20.1M
Resource for Nonhuman Primate Cell Depleting AntibodiesR24OD010976 · OD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ENGELMAN, KATHLEEN, MAGNANI, DIOGO · 2012 to 2019
$4.7M
Animal Models of Infectious Diseases Training ProgramT32AI060555 · NIAID · UNIVERSITY OF CALIFORNIA DAVIS · PI MCSORLEY, STEPHEN J · 2004 to 2025
$3.3M
Role of female genital mucosa associated CD4 T cells in vaccine-induced HIV susceptibilityR21AI143454 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI IYER, SWAMINATHAN SMITA · 2019 to 2020
$623k
NIAID NIH HHS R21 AI143454NIAID NIH HHS T32 AI060555NIAID NIH HHS U24 AI126683NIH HHS R24 OD010976
6 · The paper itself

Abstract

CD4 T follicular helper (T

Identifiers

PMID32676606
PMCPMC7359530
OpenAlexW3040975424

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.