Evidence map›Paper›PMID 32676602›Full record

ArticlebioRxiv : the preprint server for biology2020

Severely ill COVID-19 patients display augmented functional properties in SARS-CoV-2-reactive CD8

Anthony Kusnadi, Ciro Ramírez-Suástegui, Vicente Fajardo, Serena J Chee, Benjamin J Meckiff, Hayley Simon, Emanuela Pelosi, Grégory Seumois, Ferhat Ay, Pandurangan Vijayanand and 1 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Anthony KusnadiLa Jolla Institute for Immunology, La Jolla, CA, USA.
Ciro Ramírez-SuásteguiLa Jolla Institute for Immunology, La Jolla, CA, USA.
Vicente FajardoLa Jolla Institute for Immunology, La Jolla, CA, USA.
Serena J CheeNIHR and CRUK Southampton Experimental Cancer Medicine Center, Faculty of Medicine, University of Southampton, Southampton, UK.
Benjamin J MeckiffLa Jolla Institute for Immunology, La Jolla, CA, USA.
Hayley SimonLa Jolla Institute for Immunology, La Jolla, CA, USA.
Emanuela PelosiSouthampton Specialist Virology Centre, Department of Infection, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Grégory SeumoisLa Jolla Institute for Immunology, La Jolla, CA, USA.
Ferhat AyLa Jolla Institute for Immunology, La Jolla, CA, USA.
Pandurangan VijayanandLa Jolla Institute for Immunology, La Jolla, CA, USA.
Christian H OttensmeierLa Jolla Institute for Immunology, La Jolla, CA, USA.
La Jolla Institute for Immunology · USAmerican Jewish Joint Distribution Committee · USUniversity Hospital Southampton NHS Foundation Trust · GB

Funding

Single-cell atlas of lung tissue-resident memory T cells reactive to upper and lower respiratory tract pathogensU19AI118626 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI Alessandro Sette · 2015 to 2026
$36.7M
T follicular helper (Tfh) CD4+ T cell, germinal center, and antibody response dysfunction in human recurrent tonsillitisU19AI142742 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI Shane P Crotty · 2019 to 2026
$32.8M
Epigenomics of T cells and innate immune cells in human asthmaR01HL114093 · NHLBI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI ARSHAD, SYED HASAN, PETERS, BJOERN · 2011 to 2020
$8.5M
Studying the function of human genetic variation in the light of 3D genome organizationR35GM128938 · NIGMS · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI Ferhat Ay · 2018 to 2026
$4.6M
NovaSeq5000 High Throughput SequencerS10OD025052 · OD · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI SEUMOIS, GREGORY · 2018 to 2018
$832k
FACSAria II Cell SorterS10RR027366 · NCRR · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 2011 to 2011
$514k
NCRR NIH HHS S10 RR027366NHLBI NIH HHS R01 HL114093NIAID NIH HHS U19 AI118626NIAID NIH HHS U19 AI142742NIGMS NIH HHS R35 GM128938NIH HHS S10 OD025052
6 · The paper itself

Abstract

The molecular properties of CD8

Identifiers

PMID32676602
PMCPMC7359524
OpenAlexW3041700212

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.