Evidence map›Paper›PMID 32676580›Full record

ArticleFASEB bioAdvances2020

Nerve growth factor and its receptor tyrosine kinase TrkA are overexpressed in cervical squamous cell carcinoma.

Sam Faulkner, Nathan Griffin, Christopher W Rowe, Phillip Jobling, Janine M Lombard, Sonia M Oliveira, Marjorie M Walker, Hubert Hondermarck

Open access · goldAbstract read
In one paragraph

Article in FASEB bioAdvances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. The Role of the Neurotrophin Network in Skin Squamous Cell Cancer and the Novel Use of the Zebrafish System.JID innovations : skin science from molecules to population health · 2024
    Review
  7. Article
  8. Review
  9. Analysis of CD74 Occurrence in Oncogenic Fusion Proteins.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Stress Hormones: Emerging Targets in Gynecological Cancers.Frontiers in cell and developmental biology · 2021
    Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sam FaulknerSchool of Biomedical Sciences and Pharmacy Faculty of Health and Medicine University of Newcastle Callaghan NSW Australia.
Nathan GriffinSchool of Biomedical Sciences and Pharmacy Faculty of Health and Medicine University of Newcastle Callaghan NSW Australia.
Christopher W RoweHunter Medical Research Institute University of Newcastle New Lambton NSW Australia.
Phillip JoblingSchool of Biomedical Sciences and Pharmacy Faculty of Health and Medicine University of Newcastle Callaghan NSW Australia.
Janine M LombardSchool of Medicine and Public Health Faculty of Health and Medicine University of Newcastle Callaghan NSW Australia.
Sonia M OliveiraHunter Medical Research Institute University of Newcastle New Lambton NSW Australia.
Marjorie M WalkerHunter Medical Research Institute University of Newcastle New Lambton NSW Australia.
Hubert HondermarckSchool of Biomedical Sciences and Pharmacy Faculty of Health and Medicine University of Newcastle Callaghan NSW Australia.
Hunter Medical Research Institute · AUUniversity of Newcastle Australia · AUCalvary Mater Newcastle Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nerve growth factor (NGF) and its receptors are increasingly implicated in cancer progression, but their expression in cervical cancer is unclear. The objective of this study was to define the protein expression of NGF, its precursor (proNGF), as well as their receptors, the tyrosine kinase receptor TrkA, the common neurotrophin receptor p75

Indexed as

cervical cancernervesNGFp75NTRproNGFsortilin

Identifiers

PMID32676580
PMCPMC7354692
OpenAlexW3032753267

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.