Evidence map›Paper›PMID 32676439›Full record

ReviewTranslational andrology and urology2020

Targeting the cancer lesion, not the whole prostate.

Nishant Bedi, Deepika Reddy, Hashim U Ahmed

Abstract readReview
In one paragraph

Review in Translational andrology and urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
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  6. Article
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  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nishant BediImperial Urology, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK.
Deepika ReddyImperial Urology, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK.
Hashim U AhmedImperial Urology, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK.

Funding

Wellcome Trust 204998/Z/16/Z
6 · The paper itself

Abstract

Modern cancer treatment aims to conserve as much healthy tissue as possible. This has been challenging in the treatment of prostate cancer due to the difficulty in imaging the gland and concerns over leaving multifocal cancer untreated. With improvements in imaging and understanding of multifocal prostate cancer evidence now shows accurate treatment of just the primary focus of cancer or the index lesion can control progression or recurrence of the disease. Many different energy sources are now available to target the cancer lesion within the prostate with less significant side-effects on urinary and sexual function compared to radical treatment. Evidence shows that men value these functions highly and would even trade years of life in exchange for preserved retention of continence or erectile function. Focal treatment of prostate cancer aims to provide both cancer control and preservation of sexual and urinary functions so that men do not have to make a choice between the two. This is a treatment option that men clearly want and deserve.

Indexed as

cryotherapyfocal brachytherapyfocal radiofrequency ablation (focal RFA)focal therapyhigh-intensity focused ultrasound (HIFU)index lesionirreversible electroporation (IRE)laser interstitial therapy (LITT)photodynamic therapy (PDT)Prostate cancervascular-targeted photodynamic therapy (VTP)

Identifiers

PMID32676439
PMCPMC7354301

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.