Evidence map›Paper›PMID 32676437›Full record

ReviewTranslational andrology and urology2020

Value of systematic sampling in an mp-MRI targeted prostate biopsy strategy.

Martin J Connor, Saiful Miah, Rajiv Jayadevan, Christopher C Khoo, David Eldred-Evans, Taimur Shah, Hashim U Ahmed, Leonard Marks

Abstract readReview
In one paragraph

Review in Translational andrology and urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Landmarks in the evolution of prostate biopsy.Nature reviews. Urology · 2023
    Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Martin J ConnorImperial Prostate, Division of Surgery, Department of Surgery and Cancer, Imperial College, London, UK.
Saiful MiahDepartment of Urology, Cambridge University Hospitals, Hills Road, Cambridge, U.K.
Rajiv JayadevanDepartment of Urology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Christopher C KhooImperial Prostate, Division of Surgery, Department of Surgery and Cancer, Imperial College, London, UK.
David Eldred-EvansImperial Prostate, Division of Surgery, Department of Surgery and Cancer, Imperial College, London, UK.
Taimur ShahImperial Prostate, Division of Surgery, Department of Surgery and Cancer, Imperial College, London, UK.
Hashim U AhmedImperial Prostate, Division of Surgery, Department of Surgery and Cancer, Imperial College, London, UK.
Leonard MarksDepartment of Urology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

Funding

Wellcome Trust 204998/Z/16/Z
6 · The paper itself

Abstract

The clinical utility of systematic prostate biopsy in addition to multi-parametric magnetic resonance imagining (mp-MRI) targeted biopsy pathways remains unclear. Despite radiological advancements in mp-MRI and utilisation of international standardised reporting systems (i.e., PI-RADS, LIKERT), undetected clinically significant prostate cancer (csPCa) on imaging persists. This has prevented the widespread adoption of an exclusively targeted biopsy approach. The current evidence on csPCa cancer detection rates in mp-MRI targeted alone and combined with a non-targeted systematic sampling is presented. Arguments for and against routine limited systematic sampling as an adjunct to an mp-MRI targeted biopsy are discussed. Our review will report the clinical utility of a combined sampling strategy on csPCa detection rate. The available evidence suggests that we are yet to reach a stage where non-targeted systematic prostate biopsy can be routinely omitted in mp-MRI targeted prostate biopsy pathways. Research should focus on improving the accuracy of mp-MRI, prostate biopsy techniques, and in identifying those men that will most benefit from a combined prostate biopsy. Such strategies may help future urologists reduce the burden of non-targeted cores in modern mp-MRI prostate biopsy pathways.

Indexed as

biopsygradingmagnetic resonance imagining (MRI)Prostate cancerprostate neoplasm

Identifiers

PMID32676437
PMCPMC7354323

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.