Evidence map›Paper›PMID 32676410›Full record

ArticleTranslational andrology and urology2020

Survival benefit of neoadjuvant chemotherapy in pathologic T2N0 or lower urothelial carcinoma patients: evidence to support the use of neoadjuvant chemotherapy.

Hyeong Dong Yuk, Chang Wook Jeong, Cheol Kwak, Hyeon Hoe Kim, Ja Hyeon Ku

Abstract read
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Article in Translational andrology and urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hyeong Dong YukDepartment of Urology, Seoul National University Hospital, Seoul, Korea.
Chang Wook JeongDepartment of Urology, Seoul National University Hospital, Seoul, Korea.
Cheol KwakDepartment of Urology, Seoul National University Hospital, Seoul, Korea.
Hyeon Hoe KimDepartment of Urology, Seoul National University Hospital, Seoul, Korea.
Ja Hyeon KuDepartment of Urology, Seoul National University Hospital, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the survival benefit of neoadjuvant chemotherapy (NAC) in pathologic T2N0 or less patients.

methodsA total of 526 patients with less than pT2N0 underwent radical cystectomy. Patients were divided into three groups: non-NAC, those who did not receive NAC; partial NAC, those who received less 3 cycles of NAC; and complete NAC, those who received 3 cycles of NAC.

resultsMedian follow up was 74.6 (range, 24-311) months. Recurrent-free survival (RFS) was significantly (P=0.041) higher in the non-NAC group than that in the complete NAC group. Overall survival (OS) was significantly (P=0.039) higher in the non-NAC group than that in the complete NAC group. There was no significant difference between the partial NAC group and the complete NAC group. In patients with pT0, the NAC group had higher pT0 ratio than the non-NAC group (33.3%

conclusionsPatients with pT2 or lower underwent NAC showed similar prognosis as patients with pT2 or lower who did not undergo NAC.

Indexed as

Bladder cancerchemotherapyneoadjuvant chemotherapy (NAC)radical cystectomyurothelial carcinoma (UC)

Identifiers

PMID32676410
PMCPMC7354338

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