Evidence map›Paper›PMID 32676406›Full record

ArticleTranslational andrology and urology2020

Acute kidney injury in solitary kidney patients after partial nephrectomy: incidence, risk factors and prediction.

Kun Zhu, Haifeng Song, Zhenan Zhang, Binglei Ma, Xiaoyuan Bao, Qian Zhang, Jie Jin

Open access · diamondAbstract read
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Article in Translational andrology and urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kun ZhuDepartment of Urology, Peking University First Hospital, Beijing 100034, China.
Haifeng SongDepartment of Urology, Peking University First Hospital, Beijing 100034, China.
Zhenan ZhangDepartment of Urology, Peking University First Hospital, Beijing 100034, China.
Binglei MaDepartment of Urology, Peking University First Hospital, Beijing 100034, China.
Xiaoyuan BaoMedical Informatics Center, Peking University Health Science Center, Beijing 100191, China.
Qian ZhangDepartment of Urology, Peking University First Hospital, Beijing 100034, China.
Jie JinDepartment of Urology, Peking University First Hospital, Beijing 100034, China.
National Clinical Research Center for Digestive Diseases · CNPeking University · CNPeking University First Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo analyze the incidence and risk factors of acute kidney injury (AKI) after partial nephrectomy (PN) in patients with solitary kidney, and to build AKI prediction models using logistic regression and machine learning (ML) approaches.

methodsClinical data of 87 solitary kidney patients with renal mass who received PN from January 2003 to March 2019 were collected. The diagnosis of AKI was based on KDIGO criteria. Logistic regression analysis and ML method were used to build prediction models.

resultsAKI developed in 52 (59.8%) patients. The logistic regression model had three variables: ischemia time (P=0.003), surgery time (P=0.001) and preoperative fasted blood glucose level (FBG) (P=0.049). The area under curve (AUC) was 0.826, with the specificity and sensitivity of optimal threshold value 82.9% and 69.2%. The ML model had the following variables: ischemia time, surgery time, age, FBG, mean arterial pressure (MAP), colloid, crystalloid, etc. XGBoost model has the best prediction performance. The AUC was 0.749, lower than that of the logistic regression model with no statistical difference (P=0.258), with the specificity and sensitivity 62.9% and 84.6%, respectively.

conclusionsThe incidence of AKI after PN in patients with a solitary kidney was relatively high, it was associated with longer ischemia time, surgery time and higher FBG level, etc. The performance of ML model had no significant difference with logistic regression model. Prospective studies with larger sample sizes are awaited to test and verify our research findings.

Indexed as

Acute kidney injury (AKI)machine learning (ML)partial nephrectomy (PN)prediction modelsolitary kidney

Identifiers

PMID32676406
PMCPMC7354300
OpenAlexW3018943297

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.