ReviewJournal of ophthalmology2020
The Potential of Virtual Reality for Inducing Neuroplasticity in Children with Amblyopia.
Review in Journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05620173 ('Validation and Development of New Dichoptic VR-gaming Method to Treat Childhood Amblyopia; Vedea Amblyopia Therapy), which is not on this map. Cited by 30 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
'Validation and Development of New Dichoptic VR-gaming Method to Treat Childhood Amblyopia; Vedea Amblyopia Therapy (VAT)
Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- A systematic review: Virtual-reality-based techniques for human exercises and health improvement.Frontiers in public health · 2023Pooled it
- Analysis of patient adherence to emerging treatment tools for improving visual functions in amblyopia: A systematic review and meta-analysis.Journal of optometryPooled it
- Treatment strategies for amblyopia in adults: an overview of conventional methods and new technologies.Romanian journal of ophthalmologyPooled it
- NEIVATECH pilot study: immersive virtual reality training in older amblyopic children with non-compliance or non-response to patching.Scientific reports · 2024Trial
- Comparison of compliance among patients with pediatric amblyopia undergoing virtual reality-based and traditional patching method training.Frontiers in public health · 2022Trial
- Advances in behavioral vision training for the treatment of childhood amblyopia: a narrative review.Translational pediatrics · 2026Review
- Recovery of depth perception in adults with abnormal binocular vision.Vision research · 2026Article
- Virtual Reality-Based Program for Pediatric Patients With Amblyopia: Protocol for a Multicenter, Randomized, Open-Label, Two-Arm Study.JMIR research protocols · 2026Article
- Effectiveness of Active Vision Therapy in Children with Bilateral Refractive Amblyopia.Journal of ophthalmic & vision research · 2026Article
- Digital therapy using dichoptic visual perceptual learning to improve stereopsis in children with intermittent exotropia.Frontiers in digital health · 2026Article
- Relumino mode may provide video terminal assistance for the amblyopic patients.Scientific reports · 2025Article
- Effect of Fresnel prism in small-angle esotropia (≤ 20 prism diopters) with fixation preference.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Evaluation of monocular and binocular contrast perception on virtual reality head-mounted displays.Journal of medical imaging (Bellingham, Wash.) · 2024Article
- Advanced Visualization Engineering for Vision Disorders: A Clinically Focused Guide to Current Technology and Future Applications.Annals of biomedical engineering · 2024Review
- Diagnostic accuracy of a modularized, virtual-reality-based automated pupillometer for detection of relative afferent pupillary defect in unilateral optic neuropathies.Frontiers in ophthalmology · 2024Article
- Factors affecting the benefit of glasses alone in treating childhood amblyopia: an analysis of PEDIG data.BMC ophthalmology · 2023Article
- Virtual Reality Technology to Enhance Conventional Rehabilitation Program: Results of a Single-Blind, Randomized, Controlled Pilot Study in Patients with Global Developmental Delay.Journal of clinical medicine · 2023Article
- Applications and implications for extended reality to improve binocular vision and stereopsis.Journal of vision · 2023Article
- The Study of Short-Term Plastic Visual Perceptual Training Based on Virtual and Augmented Reality Technology in Amblyopia.Journal of ophthalmology · 2022Article
- Gaming Technology for Pediatric Neurorehabilitation: A Systematic Review.Frontiers in pediatrics · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, virtual reality (VR) has emerged as a new safe and effective tool for neurorehabilitation of different childhood and adulthood conditions. VR-based therapies can induce cortical reorganization and promote the activation of different neuronal connections over a wide range of ages, leading to contrasted improvements in motor and functional skills. The use of VR for the visual rehabilitation in amblyopia has been investigated in the last years, with the potential of using serious games combining perceptual learning and dichoptic stimulation. This combination of technologies allows the clinician to measure, treat, and control changes in interocular suppression, which is one of the factors leading to cortical alterations in amblyopia. Several clinical researches on this issue have been conducted, showing the potential of promoting visual acuity, contrast sensitivity, and stereopsis improvement. Indeed, several systems have been evaluated for amblyopia treatment including the use of different commercially available types of head mounted displays (HMDs). These HMDs are mostly well tolerated by patients during short exposures and do not cause significant long-term side effects, although their use has been occasionally associated with some visual discomfort and other complications in certain types of subjects. More studies are needed to confirm these promising therapies in controlled randomized clinical trials, with special emphasis on the definition of the most adequate planning for obtaining an effective recovery of the visual and binocular function.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.