Evidence map›Paper›PMID 32676079›Full record

ArticleFrontiers in immunology2020

Contactin-1 Is Required for Peripheral Innervation and Immune Homeostasis Within the Intestinal Mucosa.

Marisol Veny, Daniela Grases, Karolina Kucharova, Wai Wai Lin, Jennifer Nguyen, Sarah Huang, Carl F Ware, Barbara Ranscht, John R Šedý

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Time-resolved morphological and transcriptomic characterization of early enteric neuron subtype emergence in chick.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  9. Inflammation-relevant microbiome signature of the stroke brain, gut, spleen, and thymus and the impact of exercise.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
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  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Marisol VenyInfectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, United States.
Daniela GrasesNeuroscience and Aging Research Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, United States.
Karolina KucharovaInfectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, United States.
Wai Wai LinInfectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, United States.
Jennifer NguyenInfectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, United States.
Sarah HuangInfectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, United States.
Carl F WareInfectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, United States.
Barbara RanschtNeuroscience and Aging Research Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, United States.
John R ŠedýInfectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, United States.
Sanford Burnham Prebys Medical Discovery Institute · USDiscovery Institute · US

Funding

Mucosal Immune Defense Mechanisms of the Urinary BladderU01AI095542 · NIAID · WASHINGTON UNIVERSITY · PI COLONNA, MARCO, HULTGREN, SCOTT J. · 2011 to 2020
$9.8M
Virology CoreP01CA177322 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WU, TING-TING · 2014 to 2018
$8.7M
Anti-herpesvirus Signaling by LTalphabeta/LIGHT CytokinesR01AI048073 · NIAID · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI WARE, CARL F · 2001 to 2016
$7.0M
HVEM-BTLA system in InflammationR01AI067890 · NIAID · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI WARE, CARL F · 2007 to 2016
$4.3M
HVEM-BTLA Pathway in LymphomaR01CA164679 · NCI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI WARE, CARL F · 2012 to 2016
$2.0M
Development of Peptide Targeting Technology for Demyelinating LesionsR21NS098400 · NINDS · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI RANSCHT, BARBARA · 2016 to 2017
$536k
Adiponectin Functions in HippocampusR21MH103861 · NIMH · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI RANSCHT, BARBARA · 2014 to 2015
$536k
American Heart Association-American Stroke Association 14BGIA20380277NCI NIH HHS P01 CA177322NCI NIH HHS R01 CA164679NIAID NIH HHS R01 AI048073NIAID NIH HHS R01 AI067890NIAID NIH HHS U01 AI095542NIMH NIH HHS R21 MH103861NINDS NIH HHS R21 NS098400
6 · The paper itself

Abstract

Neuronal regulation of diverse physiological functions requires complex molecular interactions in innervated tissues to maintain proper organ function. Here we show that loss of the neuronal cell surface adhesion/recognition molecule Contactin-1 (

Indexed as

AnimalsBiomarkersBlood Cell CountBlood Chemical AnalysisContactin 1Flow CytometryGene Expression ProfilingGlucocorticoidsHomeostasisIntestinal MucosaMiceMice, KnockoutPhenotypeSignal TransductionSpleenThymus GlandBiomarkersContactin 1Glucocorticoidscontactin-1hypothalamus pituitary adrenal (HPA) axisimmune homeostasismucosal immunityneuro-immune crosstalksmall intestineT cellvilli

Identifiers

PMID32676079
PMCPMC7333639
OpenAlexW3037502159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.